Protein Alignment CG30059 and IDS

DIOPT Version :9

• Sequence 1: NP_610872.1
• Gene: CG30059 / 246425
• FlyBaseID: FBgn0260475
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_000193.1
• Gene: IDS / 3423
• HGNCID: 5389
• Length: 550
• Species: Homo sapiens
• Alignment Length: 561
• Identity: 132/561 - (23%)
• Similarity: 209/561 - (37%)
• Gaps: 139/561 - (24%)

  Fly     8 IVLVLACL-------GNTASEKLPNILLILSDDQDVELRGMF----PMEHTIEMLGFGGALFHNA 61
            :||...|:       .|:.::.| |:|||:.||....| |.:    .....|:.|.....||.||
Human    15 LVLSSVCVALGSETQANSTTDAL-NVLLIIVDDLRPSL-GCYGDKLVRSPNIDQLASHSLLFQNA 77

  Fly    62 YTPSPICCPARTSLLTGMYAHNHGTRNNSVSGGCYGPHWR-RALEPRALPYILQQHGYNTFFGGK 125
            :....:|.|:|.|.||       |.|.::.....:..:|| .|.....:|...:::||.|...||
Human    78 FAQQAVCAPSRVSFLT-------GRRPDTTRLYDFNSYWRVHAGNFSTIPQYFKENGYVTMSVGK 135

  Fly   126 YLNQYWGAG---DVPKGWNNFYGLHGNSRYY--NYTLRENTGNVHY------------ESTYLSD 173
            ..:....:.   |.|..| :|...|.:|..|  ..|.|...|.:|.            |.|....
Human   136 VFHPGISSNHTDDSPYSW-SFPPYHPSSEKYENTKTCRGPDGELHANLLCPVDVLDVPEGTLPDK 199

  Fly   174 LLRDRAADFLRNATQSSEPFFAMVAPPAAHEPF---------------TPAPRHEGVFSHIEALR 223
            ...::|...|.....|:.|||..|.....|.||               |.||..|..    :.|.
Human   200 QSTEQAIQLLEKMKTSASPFFLAVGYHKPHIPFRYPKEFQKLYPLENITLAPDPEVP----DGLP 260

  Fly   224 TPSFNQVKQDKHWL-VRAARRLPNETINTIDTY------FQKR-----WETLLAVDELVVTLMGV 276
            ..::|.      |: :|  :|...:.:|....|      ||::     :.::..:|..|..|:..
Human   261 PVAYNP------WMDIR--QREDVQALNISVPYGPIPVDFQRKIRQSYFASVSYLDTQVGRLLSA 317

  Fly   277 LNDTQSLENTYIIYTSDNGYHVGQFAQPFDKRQPYETDINVPLLIRGPG---IAPES-------- 330
            |:|.|...:|.|.:|||:|:.:|:..: :.|...::...:|||:...||   ..||:
Human   318 LDDLQLANSTIIAFTSDHGWALGEHGE-WAKYSNFDVATHVPLIFYVPGRTASLPEAGEKLFPYL 381

  Fly   331 -HIDTA-------------VSLVDLAPTILAWADIDTPSYMDGQSFH-ELLLNKRRRVPFFERSL 380
             ..|:|             |.||.|.||:...|.:..|......||| ||....:..:..|....
Human   382 DPFDSASQLMEPGRQSMDLVELVSLFPTLAGLAGLQVPPRCPVPSFHVELCREGKNLLKHFRFRD 446

  Fly   381 LIEYWGEGTLATFNPECPWPEKDRLA--QCTPAADCHCQDAWNNTYACLRNIR----------HR 433
            |.|          :|..|...::.:|  |....:|.   ..||:....|::|:          :|
Human   447 LEE----------DPYLPGNPRELIAYSQYPRPSDI---PQWNSDKPSLKDIKIMGYSIRTIDYR 498

  Fly   434 EDRIYCEFRDNE---NFL-----EAYDLQLDPFQMTNIAYD 466
            . .::..|..:|   ||.     |.|.:..||.|..|:..|
Human   499 Y-TVWVGFNPDEFLANFSDIHAGELYFVDSDPLQDHNMYND 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30059	NP_610872.1	G6S	24..467	CDD:293766	127/538 (24%)
		AslA	24..464	CDD:225661	126/534 (24%)
IDS	NP_000193.1	AslA	33..544	CDD:225661	128/543 (24%)
		iduronate-2-sulfatase	38..540	CDD:293754	127/537 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900