DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30059 and CG32191

DIOPT Version :9

Sequence 1:	NP_610872.1	Gene:	CG30059 / 246425	FlyBaseID:	FBgn0260475	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_001287102.1	Gene:	CG32191 / 317903	FlyBaseID:	FBgn0052191	Length:	564	Species:	Drosophila melanogaster

Alignment Length:	569	Identity:	135/569 - (23%)
Similarity:	218/569 - (38%)	Gaps:	158/569 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LVLACL-----GNTASEKLPNILLILSDD---QDVELRG----MFPMEHTIEMLGFGGALFHNAY 62
            |:|.||     ..:|:.:.|||::|::||   .||..||    :.|   .|:.|.:.|.|....|
  Fly     8 LLLLCLQRVKSDESAAARRPNIIIIMADDMGFDDVSFRGGREFLTP---NIDALAYHGRLLDRLY 69

  Fly    63 TPSPICCPARTSLLTGMYAHNHGTRNNSVSGGCYGPHWRRALEPRALPYILQQHGYNTFFGGK-- 125
            .|: :|.|:|.:||:|.|..:.||::..:|.   ...|...|....:|.|.::.||:|...||
  Fly    70 APA-MCTPSRGALLSGRYPIHTGTQHFVISN---EEPWALTLNATLMPEIFKEAGYSTNLVGKWH 130

  Fly   126 ----------------YLNQYWGAGDVPKGWNNFYGLHGNSRYYNYTL-RENTGNVHYE----ST 169
                            |...||||      :.:::.........||:| .:...|:..|    ..
  Fly   131 LGFSRPEYTPTRRGFDYHFGYWGA------YIDYFQRRSKMPVANYSLGYDFRRNMELECRDRGV 189

  Fly   170 YLSDLLRDRAADFLRNATQSSEPFFAMVAPPAAH-----EPFTPAPRHEGVFSHIEALRTPSFNQ 229
            |::|||...|...:::.....:|.|.|::..|||     :|. .||..|          ...|:.
  Fly   190 YVTDLLTAEAERLIKDHADKEQPLFLMLSHLAAHTANEDDPL-QAPEEE----------IQKFSY 243

  Fly   230 VKQDKHWLVRAARRLPNETINTIDTYFQKRWETLLA-VDELVVTLMGVLNDTQSLENTYIIYTSD 293
            :|.            ||          ::::..::: :|:.|..::..|:.|..|||:.:|:.||
  Fly   244 IKD------------PN----------RRKYAAMISKLDQSVGRIITALSSTDQLENSIVIFYSD 286

  Fly   294 NGY-HVGQFAQ-----PF--DKRQPYETDINVPLLIRGPGI-APESHIDTAVSLVDLAPTILAWA 349
            ||. .||.|:.     |.  .|..|:|..:.|...|...|: |..|.....:.:.|..||:...|
  Fly   287 NGAPSVGMFSNTGSNFPLRGQKNTPWEGGVRVAGAIWSSGLQARGSIFRQPLYVADWLPTLSRAA 351

  Fly   350 DI--DTPSYMDGQSFHELLLNK--RRRVPFFERSLLIEYW-------GE-----GTLAT--FNPE 396
            ||  |:...:||......|...  ...||.....:|.:.|       |:     ||.|:  ::..
  Fly   352 DIELDSSLKLDGIDLWPELSGSADAPHVPREILHILDDVWRLSALQMGQWKYVNGTTASGRYDSV 416

  Fly   397 CPWPEKDRLAQCTPAADCHCQDAWNNTYA-CLRN---------------------IRHREDRIYC 439
            ..:.|.|.|            |..::.|| .:||                     :..|...:.|
  Fly   417 LTYRELDDL------------DPRDSRYAVTVRNSATSRALSRYDLRRLTQQRISLTRRLAAVRC 469

  Fly   440 E--FRDNENFLE--AYDLQLDPFQMTNIAYD------LLPIERALYSLR 478
            .  .|.....||  .||:..||.:..|:.|.      |..:.|.:..||
  Fly   470 GDLQRSCNPLLEECLYDILSDPCEQNNLVYSERHSDVLTALRRRVQELR 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30059	NP_610872.1	G6S	24..467	CDD:293766	126/537 (23%)
CG30059	NP_610872.1	AslA	24..464	CDD:225661	125/528 (24%)
CG32191	NP_001287102.1	AslA	23..458	CDD:225661	115/492 (23%)
		4-S	27..408	CDD:293753	105/426 (25%)
		DUF4976	<478..540	CDD:303608	12/41 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466494
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830