DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30059 and Gns

DIOPT Version :9

Sequence 1:	NP_610872.1	Gene:	CG30059 / 246425	FlyBaseID:	FBgn0260475	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	XP_006241458.1	Gene:	Gns / 299825	RGDID:	1305877	Length:	544	Species:	Rattus norvegicus

Alignment Length:	498	Identity:	226/498 - (45%)
Similarity:	303/498 - (60%)	Gaps:	23/498 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LIVLVLACLGNTASEKLPNILLILSDDQDVELRGMFPMEHTIEMLGFGGALFHNAYTPSPICCPA 71
            |:.|:..|||...:.:.||:||:|:||||.||.||.|::.|..::|..|..|.:||.||.:|||:
  Rat    22 LLPLLSGCLGLVGAARRPNVLLLLTDDQDAELGGMTPLKKTKALIGEKGMTFSSAYVPSALCCPS 86

  Fly    72 RTSLLTGMYAHNHGTRNNSVSGGCYGPHWRRALEPRALPYILQ-QHGYNTFFGGKYLNQYWGAGD 135
            |.|:|||.|.|||...||::.|.|....|::..||...|.||: ..||.|||.|||||:| ||.|
  Rat    87 RASILTGKYPHNHHVVNNTLEGNCSSKSWQKIQEPYTFPAILKLVCGYQTFFAGKYLNEY-GAPD 150

  Fly   136 ------VPKGWNNFYGLHGNSRYYNYTLRENTGNV-----HYESTYLSDLLRDRAADFLRNATQS 189
                  ||.||:.:|.|..||:||||||..| |..     :|...||:|:|.:.:.||| :...:
  Rat   151 AGGLEHVPLGWSYWYALEKNSKYYNYTLSIN-GKARRHGENYSVDYLTDVLANLSLDFL-DYKSN 213

  Fly   190 SEPFFAMVAPPAAHEPFTPAPRHEGVFSHIEALRTPSFNQVKQDKHWLVRAARR-LPNETINTID 253
            |||||.|::.||.|.|:|.||:::..|.::.|.|..:||....:||||:|.|:. :.|.:|..:|
  Rat   214 SEPFFMMISTPAPHSPWTAAPQYQKAFPNVIAPRNKNFNIHGTNKHWLIRQAKTPMTNSSIKFLD 278

  Fly   254 TYFQKRWETLLAVDELVVTLMGVLNDTQSLENTYIIYTSDNGYHVGQFAQPFDKRQPYETDINVP 318
            ..|::||:|||:||:||..|:..|:.|..|:||||.||||||||.|||:.|.||||.||.||.||
  Rat   279 DAFRRRWQTLLSVDDLVEKLVKRLDSTGELDNTYIFYTSDNGYHTGQFSLPIDKRQLYEFDIKVP 343

  Fly   319 LLIRGPGIAPESHIDTAVSLVDLAPTILAWADID-TPSYMDGQSFHELLLNKRRRVPFFERSLLI 382
            ||:|||||.|.......||.:||.||||..|..| ..:.|||.|...:|.......  :...:|:
  Rat   344 LLVRGPGIKPNQTSKMLVSNIDLGPTILDLAGYDLNKTQMDGTSLLPILKGDGNLT--WRSDVLV 406

  Fly   383 EYWGEGTLATFNPECPWPEKDRLAQCTPAADCHCQDAWNNTYACLRNIRHREDRIYCEFRDNENF 447
            ||.|||...| :|.|| .....::||.|  ||.|:||:||||||:|.:....:..||||.|.|.|
  Rat   407 EYQGEGRNVT-DPTCP-SLSPGVSQCFP--DCVCEDAYNNTYACVRTLSSMWNLQYCEFDDQEVF 467

  Fly   448 LEAYDLQLDPFQMTNIAYDLLPIERALYSLRLKNLTQCSGHSC 490
            :|.|::..||.|:||||..:.|......:.||..|..|||.:|
  Rat   468 VEVYNITADPDQITNIAKSIDPELLGKMNYRLMMLQSCSGPTC 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30059	NP_610872.1	G6S	24..467	CDD:293766	213/456 (47%)
CG30059	NP_610872.1	AslA	24..464	CDD:225661	211/453 (47%)
Gns	XP_006241458.1	G6S	38..487	CDD:293766	213/457 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351100
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H1568
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1273622at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_103483
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.740