DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30059 and Sulf1

DIOPT Version :9

Sequence 1:	NP_610872.1	Gene:	CG30059 / 246425	FlyBaseID:	FBgn0260475	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	XP_006495573.1	Gene:	Sulf1 / 240725	MGIID:	2138563	Length:	1121	Species:	Mus musculus

Alignment Length:	573	Identity:	178/573 - (31%)
Similarity:	262/573 - (45%)	Gaps:	140/573 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LIVLVLACLGNTASEKL---------------------PNILLILSDDQDVELRGMFPMEHTIEM 50
            |..|:||.||......|                     |||:|:|:|||||||..:..|..|.::
Mouse     5 LWALLLAVLGTQLLGSLCSTVRSQRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVMNKTRKI 69

  Fly    51 LGFGGALFHNAYTPSPICCPARTSLLTGMYAHNHGTRNNSVSGGCYGPHWRRALEPRALPYILQQ 115
            :..|||.|.||:..:|:|||:|:|:|||.|.|||....|:.:  |..|.|:...|||.....|..
Mouse    70 MEQGGATFTNAFVTTPMCCPSRSSMLTGKYVHNHNVYTNNEN--CSSPSWQAMHEPRTFAVYLNN 132

  Fly   116 HGYNTFFGGKYLNQYWGAGDVPKGWNNFYGLHGNSRYYNYT-----LRENTGNVHYESTYLSDLL 175
            .||.|.|.|||||:|.|: .:|.||..:.||..|||:||||     ::|..| ..|...|.:||:
Mouse   133 TGYRTAFFGKYLNEYNGS-YIPPGWREWLGLIKNSRFYNYTVCRNGIKEKHG-FDYAKDYFTDLI 195

  Fly   176 RDRAADFLRNATQ--SSEPFFAMVAPPAAHEPFTPAPRHEGVFSHIEALRTPSFNQV-KQDKHWL 237
            .:.:.::.:.:.:  ...|...:::..|.|.|...||:...::.:.....|||:|.. ..||||:
Mouse   196 TNESINYFKMSKRMYPHRPIMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWI 260

  Fly   238 VR-AARRLP--NETINTIDTYFQKRWETLLAVDELVVTLMGVLNDTQSLENTYIIYTSDNGYHVG 299
            :: ....||  .|..|.:.   :||.:||::||:.|..|..:|.::..|:|||||||:|:|||:|
Mouse   261 MQYTGPMLPIHMEFTNVLQ---RKRLQTLMSVDDSVERLYNMLVESGELDNTYIIYTADHGYHIG 322

  Fly   300 QFAQPFDKRQPYETDINVPLLIRGPGIAPESHIDTAVSLVDLAPTILAWADIDTPSYMDGQSFHE 364
            ||.....|..||:.||.||..||||.|.|.|.:...|..:|||||||..|.:|:||.:||:|..:
Mouse   323 QFGLVKGKSMPYDFDIRVPFFIRGPSIEPGSIVPQIVLNIDLAPTILDIAGLDSPSDVDGKSVLK 387

  Fly   365 LL----------LNKRRRV-----------------------------PFFERSLLIEYWGEGTL 390
            ||          .||:.::                             |.:||  :.|...:
Mouse   388 LLDLEKPGNRFRTNKKAKIWRDTFLVERGKFLRKKEESGKNIQQSNHLPKYER--VKELCQQ--- 447

  Fly   391 ATFNPECPWPEKD-----------RLAQCTPAAD----------------------CHCQDAW-- 420
            |.:...|..|.::           |:.:|...:|                      |||:|:.
Mouse   448 ARYQTACEQPGQNWQCIEDTSGKLRIHKCKGPSDLLTVRQNARNLYSRGLHDKDKECHCRDSGYR 512

  Fly   421 ------NNTYACLRN----------IRHREDR-IYCEFRDNENFLEAYDLQLD 456
                  .|....|||          :..|:.| :..||..     |.||:.|:
Mouse   513 SSRSQRKNQRQFLRNKGTPKYKPRFVHTRQTRSLSVEFEG-----EIYDINLE 560

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30059	NP_610872.1	G6S	24..467	CDD:293766	171/535 (32%)
CG30059	NP_610872.1	AslA	24..464	CDD:225661	171/535 (32%)
Sulf1	XP_006495573.1	G6S	42..384	CDD:293766	140/348 (40%)
		DUF3740	534..674	CDD:403667	8/32 (25%)
		ALP_like	<767..816	CDD:419962
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847542
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830