DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30059 and arsb

DIOPT Version :9

Sequence 1:	NP_610872.1	Gene:	CG30059 / 246425	FlyBaseID:	FBgn0260475	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	XP_021324609.1	Gene:	arsb / 100538007	ZFINID:	ZDB-GENE-111123-2	Length:	502	Species:	Danio rerio

Alignment Length:	561	Identity:	125/561 - (22%)
Similarity:	210/561 - (37%)	Gaps:	155/561 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LIVLVLACLGNTASEKLPNILLILSDD---QDVELRGMFPMEHTIEMLGFGGALFHNAYTPSPIC 68
            |:.:||.|:    |.:.|:::|||:||   .||...|.......::.|...|....|.|. .|:|
Zfish    10 LLCVVLECV----SARPPHVVLILADDLGWNDVGFHGSEIKTPHLDRLAAQGVRLDNYYV-QPLC 69

  Fly    69 CPARTSLLTGMYAHNHGTRNNSVSGGCYGPHWR-----RALEPRALPYILQQHGYNTFFGGKYLN 128
            .|:|..|:||.|....|.::..:        |.     ..|:.:.||.:|::.||:|...||
Zfish    70 TPSRNQLMTGRYQIRTGLQHQII--------WPCQPYCVPLDEKLLPQVLRERGYHTHMVGK--- 123

  Fly   129 QYWGAGDVPK-------GWNNFYG-LHGNSRYYNY----------------TLRENTG-NVHYES 168
              |..|...|       |:.:|:| |.|:..||.:                .||:... .::|..
Zfish   124 --WHLGMFQKDCLPTHRGFQSFFGYLTGSEDYYTHKRCSPIAPLNVTRCALDLRDGDAVALNYSG 186

  Fly   169 TYLSDLLRDRAADFLRNATQSSEPFFAMVAPPAAHEPFTPAPRHEGVFSHIEALRTPSFNQVKQD 233
            .|.::||.:||...:...| ..:|.|..||..|.|.|......:...:|.|            ||
Zfish   187 RYSTELLTERATHIITQHT-PDQPLFLYVALQAVHAPLQVPDHYIAPYSFI------------QD 238

  Fly   234 KHWLVRAARRLPNETINTIDTYFQKRWETLL-AVDELVVTLMGVLNDTQSLENTYIIYTSDNG-- 295
            .|                     ::|:..:: |:||.|..:...|.:|...:||.:|:::|||
Zfish   239 PH---------------------RRRYAGMVSAMDEAVGNITHTLQETGLWDNTVLIFSTDNGGQ 282

  Fly   296 --YHVGQFAQPFDKRQPYETDINVPLLIRGPGIAPESHID-TAVSLVDLAPTI--LAWADIDTPS 355
              |....:.....|...:|..:.....:.||.|.....:: ..:.:.|..|||  ||.|..:...
Zfish   283 TLYGGNNWPLRGRKWTLWEGGVRGVAFVSGPLIEKPGAVNRELIHISDWLPTIAGLAGASTNGTK 347

  Fly   356 YMDG----QSFH--------ELLLNKRRRVPFFERSLLIEYWGEGTLATFNPECPWPE----KDR 404
            .:||    ||..        |||.|..   |.:|.|              :| ||..|    :|.
Zfish   348 PLDGFDVWQSISAGVASPRVELLHNID---PLYEDS--------------SP-CPGGEGVFLEDS 394

  Fly   405 LAQCTPAADCHCQDA---WN-NTYACLRNIRHREDRIYCEF---------------RDNENFLEA 450
            |...:.::.....|.   :| :.:|.   |||:..::...:               ..:|...:.
Zfish   395 LHSSSSSSSSSSSDVSAQFNISIHAA---IRHKNWKLLTGYPGCPLWIPPPGGRPVNASEPLKQV 456

  Fly   451 --YDLQLDPFQMTNIAYDLLPIERALYSLRLKNLTQCSGHS 489
              :|::.||.:...:::.    ...:.|..|:.|..|...:
Zfish   457 MLFDVEKDPEERLEVSHQ----RPEVVSFLLRRLQLCQNQA 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30059	NP_610872.1	G6S	24..467	CDD:293766	116/520 (22%)
CG30059	NP_610872.1	AslA	24..464	CDD:225661	116/517 (22%)
arsb	XP_021324609.1	4-S	23..472	CDD:293753	116/517 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592886
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930