DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30059 and gns

DIOPT Version :9

Sequence 1:	NP_610872.1	Gene:	CG30059 / 246425	FlyBaseID:	FBgn0260475	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_001107314.1	Gene:	gns / 100135105	XenbaseID:	XB-GENE-978429	Length:	533	Species:	Xenopus tropicalis

Alignment Length:	502	Identity:	229/502 - (45%)
Similarity:	305/502 - (60%)	Gaps:	31/502 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VLVLACLGN-----TASEKLPNILLILSDDQDVELRGMFPMEHTIEMLGFGGALFHNAYTPSPIC 68
            :|:|..||:     ....:.||::|||:|||||.|.||.|::.|.|::...|.:|.|||..|.:|
Frog    11 LLLLGLLGSLPVSVEGRSRKPNVVLILTDDQDVSLGGMTPLKKTKELIADHGMMFSNAYVASALC 75

  Fly    69 CPARTSLLTGMYAHNHGTRNNSVSGGCYGPHWRRALEPRALPYILQQHGYNTFFGGKYLNQY--- 130
            ||:|:|:|||.|.|||...||:|.|.|....|::..||...|.:|...||.|||.|||||||
Frog    76 CPSRSSILTGRYPHNHHVVNNTVEGNCSSKAWQKTQEPYTFPALLFSIGYQTFFAGKYLNQYGSE 140

  Fly   131 --WGAGDVPKGWNNFYGLHGNSRYYNYTLREN----TGNVHYESTYLSDLLRDRAADFLRNATQS 189
              .|...||.||:.::.|..||:||||||.||    |...:|...||:|:|.:.:.||| |...:
Frog   141 EAGGINHVPPGWSYWFALEKNSKYYNYTLSENGRPKTHGENYSQDYLTDVLANVSLDFL-NYKSN 204

  Fly   190 SEPFFAMVAPPAAHEPFTPAPRHEGVFSHIEALRTPSFNQVKQDKHWLVRAARR-LPNETINTID 253
            ..|||.|:|.||.|.|:|.||::|..|.::.|.|..:||...:|||||:|.|:. :.|.:|..:|
Frog   205 YAPFFMMIATPAPHSPWTAAPQYETAFLNVSAPRGSNFNVHGKDKHWLIRQAKSPMSNSSIQYLD 269

  Fly   254 TYFQKRWETLLAVDELVVTLMGVLNDTQSLENTYIIYTSDNGYHVGQFAQPFDKRQPYETDINVP 318
            ..|||||:|||:||:||..|:..|.....|:||:|.:|||||||.|||:.|.||||.||.||.||
Frog   270 NAFQKRWQTLLSVDDLVEKLVKQLEARGELDNTFIFFTSDNGYHTGQFSLPIDKRQLYEFDIKVP 334

  Fly   319 LLIRGPGIAPESHIDTAVSLVDLAPTILAWADID-TPSYMDGQSFHELLLNKRRRVPFFERSLLI 382
            ||:|||||.|.....:.|:.:||.||||..|..| ..:.|||.||..:::|...  ..:...:|:
Frog   335 LLVRGPGIKPNQITKSLVANIDLGPTILDIAGYDLNKTQMDGMSFLPVMINNSN--VNWRTDILV 397

  Fly   383 EYWGEGTLATFNPECP--WPEKDRLAQCTPAADCHCQDAWNNTYACLRNIRHREDRIYCEFRDNE 445
            ||.|||: .|.:|.||  .|   .::||.|  ||.|:|::||||||:|.|....|..||||.|.|
Frog   398 EYQGEGS-NTSDPTCPALGP---GVSQCFP--DCVCEDSYNNTYACVRTIAAAYDLQYCEFDDAE 456

  Fly   446 NFLEAYDLQLDPFQMTNIA--YDLLPIERALYSLRLKNLTQCSGHSC 490
            .|.|.|::..||.|:||||  .|...:|:..:  ||..|..|||.||
Frog   457 VFAEVYNITADPNQLTNIAKTIDQEILEKMNH--RLMMLQSCSGPSC 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30059	NP_610872.1	G6S	24..467	CDD:293766	215/457 (47%)
CG30059	NP_610872.1	AslA	24..464	CDD:225661	213/452 (47%)
gns	NP_001107314.1	G6S	30..478	CDD:293766	215/456 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H1568
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1273622at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010