Protein Alignment Tmem18 and Tmem18

DIOPT Version :9

• Sequence 1: NP_725169.3
• Gene: Tmem18 / 246418
• FlyBaseID: FBgn0050051
• Length: 151
• Species: Drosophila melanogaster
• Sequence 2: NP_742046.2
• Gene: Tmem18 / 211986
• MGIID: 2387176
• Length: 140
• Species: Mus musculus
• Alignment Length: 124
• Identity: 53/124 - (42%)
• Similarity: 74/124 - (59%)
• Gaps: 1/124 - (0%)

  Fly    18 LLSIDWKDPWLIGLILAHILTTTTALLSRNSSNFQVFLFLVLLLAVYFTESINEFAANNWSSFSR 82
            ::..||.:|||:||:..|:|.......|......|:..||.|::.||..|.|||.||.||..||:
Mouse    18 IMETDWTEPWLLGLLAFHLLCLLLTCFSSQRYKLQIGHFLCLVVLVYSAEYINEVAAVNWRLFSK 82

  Fly    83 QQYFDSNGLFISTVFSIPILLNCMLLIGTWLYNSTQLMVTLKTAQLKERARKERQTKAD 141
            .|||||.|:|||.|||.|:|.|.||::..|:..:..:|..|||.| :||..:.|:.|.:
Mouse    83 YQYFDSRGMFISLVFSAPLLFNAMLIVIMWVRKTLTVMTDLKTLQ-EERKERRRRRKEE 140

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tmem18	NP_725169.3	TMEM18	15..133	CDD:291436	51/114 (45%)
Tmem18	NP_742046.2	TMEM18	14..127	CDD:291436	48/108 (44%)
		DNA-binding. /evidence=ECO:0000250	113..140		8/26 (31%)
		Nuclear localization signal. /evidence=ECO:0000250	130..138		3/7 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830602
Domainoid	1	1.000	104	1.000	Domainoid score	I6724
eggNOG	1	0.900	-	-		E1_2AIGZ
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H17675
Inparanoid	1	1.050	108	1.000	Inparanoid score	I4903
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58005
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007148
OrthoInspector	1	1.000	-	-		oto92670
orthoMCL	1	0.900	-	-		OOG6_104718
Panther	1	1.100	-	-	LDO	PTHR22593
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4869
SonicParanoid	1	1.000	-	-		X5246
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790