Protein Alignment Tmem18 and TMEM18

DIOPT Version :9

• Sequence 1: NP_725169.3
• Gene: Tmem18 / 246418
• FlyBaseID: FBgn0050051
• Length: 151
• Species: Drosophila melanogaster
• Sequence 2: NP_001339610.1
• Gene: TMEM18 / 129787
• HGNCID: 25257
• Length: 143
• Species: Homo sapiens
• Alignment Length: 124
• Identity: 57/124 - (45%)
• Similarity: 76/124 - (61%)
• Gaps: 1/124 - (0%)

  Fly    18 LLSIDWKDPWLIGLILAHILTTTTALLSRNSSNFQVFLFLVLLLAVYFTESINEFAANNWSSFSR 82
            ||..||.:|||:||...|.|......||..|...|:..||.|::.||..|.|||.||.||..||:
Human    21 LLQTDWTEPWLMGLATFHALCVLLTCLSSRSYRLQIGHFLCLVILVYCAEYINEAAAMNWRLFSK 85

  Fly    83 QQYFDSNGLFISTVFSIPILLNCMLLIGTWLYNSTQLMVTLKTAQLKERARKERQTKAD 141
            .|||||.|:|||.|||.|:|:|.|:::..|::.:..:|..||.|| :.|..|:|:.|.|
Human    86 YQYFDSRGMFISIVFSAPLLVNAMIIVVMWVWKTLNVMTDLKNAQ-ERRKEKKRRRKED 143

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tmem18	NP_725169.3	TMEM18	15..133	CDD:291436	53/114 (46%)
TMEM18	NP_001339610.1	TMEM18	21..130	CDD:317209	50/108 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140631
Domainoid	1	1.000	107	1.000	Domainoid score	I6551
eggNOG	1	0.900	-	-		E1_2AIGZ
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	112	1.000	Inparanoid score	I4872
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58005
OrthoDB	1	1.010	-	-		D1575793at2759
OrthoFinder	1	1.000	-	-		FOG0007148
OrthoInspector	1	1.000	-	-		oto89103
orthoMCL	1	0.900	-	-		OOG6_104718
Panther	1	1.100	-	-	LDO	PTHR22593
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4869
SonicParanoid	1	1.000	-	-		X5246
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.800