Protein Alignment CG30049 and PFF1

DIOPT Version :10

• Sequence 1: NP_725142.3
• Gene: CG30049 / 246416
• FlyBaseID: FBgn0050049
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_009630.3
• Gene: PFF1 / 852366
• SGDID: S000000278
• Length: 976
• Species: Saccharomyces cerevisiae
• Alignment Length: 793
• Identity: 175/793 - (22%)
• Similarity: 288/793 - (36%)
• Gaps: 241/793 - (30%)

  Fly   150 NVVVKLSTASSNSSSYLLINSHFDTKPGSPGAGDDGTMVVVMLEVLRQMSISESEFMH----PIV 210
            |::|||...:..... ||:::|||:.|...||.|||..||.:|..|:.      ...|    .::
Yeast   136 NILVKLEGKNPEEEG-LLLSAHFDSVPTGYGATDDGMGVVSLLANLKY------HIKHRPNRTLI 193

  Fly   211 FLFNGAEENPLQASHGFITQHKWAPNCKAVINLEVGGNGGRDILFQSGPNNPWLVKYYKQHSK-H 274
            |.||..||..|..:..:. .|.|:...|.|||||..|.||:.:||::...:  ..:.|:|..| :
Yeast   194 FNFNNNEEFGLLGASTYF-DHSWSNLTKYVINLEGTGAGGKAVLFRTSDTS--TARIYQQSVKEN 255

  Fly   275 PFASTLAEEIFQFGILPSDTDFRIFRDYGNIPGLDIAQFSNGYVYHTAFDSFDVVPGRAVQNTGE 339
            ||.:::.::.|....:.|:||::|:.:.| :.|.|:|.:....:|||..||        :|.|.:
Yeast   256 PFGNSIYQQGFYSRYVRSETDYKIYEENG-MRGWDVAFYKPRNLYHTIKDS--------IQYTSK 311

  Fly   340 NIL------SLVRALSNASELYNTNEHSAGHAVFFDFLGLFFVTYTENTGIILNYCFAVASVFLV 398
            ..|      ||..:...||...:|.:.:.  |.:|||:||.|...:..|   |.|
Yeast   312 ASLWHMLHTSLQLSAYVASNSLDTADQTP--ACYFDFIGLKFFVISAKT---LFY---------- 361

  Fly   399 GFSLWRMSCVSEVSAGRISILFASHLGLHLAGCLLCIGLPLVMSILYDVSDRTMTYYSNNWLVIG 463
                |                          .|:..:..|:|...||.:|...||:.|.:||...
Yeast   362 ----W--------------------------NCIFLLVSPVVAIGLYLISRDRMTWKSYSWLSWT 396

  Fly   464 LYICPAIIGLVLPSTLYHSFKSDDKISHPYQMYVGLHAHCVVLSILTIALTAIGLRIPYMCMISL 528
            .:......|:::...    |.:|...|:|                ||.:
Yeast   397 RFPLSLAAGIIVQKL----FSNDIIRSNP----------------LTFS---------------- 425

  Fly   529 FLYILSLLINLLTTLHDRGYYWVLTVQISQLF-QYVYFCYLFYIFLVIFFPAMGRNRDSANPDM- 591
                             |.|:|    .||..| |.::..|:.......|||.         .||
Yeast   426 -----------------RNYFW----PISAFFTQVIFTSYVLINCSNFFFPC---------ADMK 460

  Fly   592 ---LIALICAVGTF------------FALGFVVPLINMFRWSTYLLICLGVVTFILSMISITGVG 641
               :|.|...:.|.            :....:.||...|..||...| |.::...|.|.:...:|
Yeast   461 SLSIIELFIILWTILLFTSKLLYSSDYRYTGLYPLSIFFLLSTIAAI-LRLLALALGMRTRKRLG 524

  Fly   642 FPYRPKTSVMRVNFLQTRRMFYEYDGSLSVND-SGYYFDYQDRRALRPLKDYAVNLT-------- 697
            ...|...|    |:....::..|.||..::.. .......||.:|  .::|..|:.|
Yeast   525 RECRDHHS----NYSSHSQIDMERDGQENLEQPQDQLTSSQDDQA--SIQDDNVSTTSAGPSHNV 583

  Fly   698 ----GLTSVDGYCDRYVMCGIPCF--WSSWCRGISSA-----------AWLPRD-EEVTVPG--- 741
                |:.|.....|..|    |..  .:|...|:|:.           ||:.:. ..|.:|.
Yeast   584 DEDHGMDSSSQQHDERV----PLLKGSNSMEEGLSTRENSLKLEYTDYAWIIQFLLIVPIPSFIL 644

  Fly   742 ----NLELNFLNKTLSKSGSSARFE---FELAGPPHMGLYIRP----LDGVAVEDWSFI------ 789
                ::.::.||.|: :.||.|.|:   |.:.|...:.|.|.|    ::.:.:...:.:
Yeast   645 FNSVDVIMDALNHTV-QEGSKATFDVLRFGMVGSILIALPILPFFYKVNYITISLTALLFLISAS 708

  Fly   790 RTMLDQPEKYSPPYQIYFSYGVDSSPFKFHIEFVKSDGQLDGPIFELGVVGHYVNQDFERDETTL 854
            :|:|..|...|.|.::.||..:|.|               .|....:.|:|        |:...|
Yeast   709 KTLLVHPFTNSNPLKVRFSQNIDLS---------------QGNAASVHVLG--------REGNFL 750

  Fly   855 R-FIADLPDFVYT 866
            : .:.|||...|:
Yeast   751 KPMLQDLPSIKYS 763

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30049	NP_725142.3	M28_Fxna_like	71..378	CDD:349872	73/238 (31%)
PFF1	NP_009630.3	M28_Fxna_like	50..354	CDD:349872	73/238 (31%)
		DUF2189	366..>443	CDD:470522	24/133 (18%)