Protein Alignment CG30049 and Ermp1

DIOPT Version :10

• Sequence 1: NP_725142.3
• Gene: CG30049 / 246416
• FlyBaseID: FBgn0050049
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: XP_006231303.1
• Gene: Ermp1 / 373544
• RGDID: 727831
• Length: 899
• Species: Rattus norvegicus
• Alignment Length: 897
• Identity: 286/897 - (31%)
• Similarity: 438/897 - (48%)
• Gaps: 126/897 - (14%)

  Fly    42 LWVALFYAIVLPLFYRLPDRVTMADEPLKPGQFVGERAQKILYELDRIGPKVVGSTANEVTTVAF 106
            |.:||:...:..|......|:.::......|:|...:|:..|..:..|||:..||..||:.||.:
  Rat    69 LALALYLLALRALVQLSLQRLVLSRTSGLQGEFDARQARVYLEHITAIGPRTTGSAENEILTVQY 133

  Fly   107 LLNEVEKIRSEMRGDLFHLEVDVQQPTGSYVV---GTMTSIYQGIQNVVVKLSTASSNSSSY-LL 167
            ||.::..| .|....|..:.||||:||||:.:   |..||.|..|.||||||.  ..:.:.| :|
  Rat   134 LLEQITLI-EEQSNSLHRISVDVQRPTGSFSIDFLGGFTSYYDNITNVVVKLE--PQDGAKYAVL 195

  Fly   168 INSHFDTKPGSPGAGDDGTMVVVMLEVLRQMSISESEFMHPIVFLFNGAEENPLQASHGFITQHK 232
            .|.|||:...||||.||.....|||||||.|:.|.....|.:||||||||||.|||||||||||.
  Rat   196 ANCHFDSVANSPGASDDAVSCAVMLEVLRVMAASPEPLQHAVVFLFNGAEENVLQASHGFITQHP 260

  Fly   233 WAPNCKAVINLEVGGNGGRDILFQSGPNNPWLVKYYKQHSKHPFASTLAEEIFQFGILPSDTDFR 297
            ||...:|.||||..|.||::::||:||.|||||:.|...:||||||.:|:|:||.||:|||||||
  Rat   261 WASLIRAFINLEAAGVGGKELVFQTGPENPWLVQAYVSAAKHPFASVVAQEVFQSGIIPSDTDFR 325

  Fly   298 IFRDYGNIPGLDIAQFSNGYVYHTAFDSFDVVPGRAVQNTGENILSLVRALSNASELYNTNEHSA 362
            |:||:|||||:|:|...|||:|||.:|:.|.:...::|..|:|||::::.|:.:..|.:::|:..
  Rat   326 IYRDFGNIPGIDLAFIENGYIYHTKYDTADRILIDSIQRAGDNILAVLKYLATSDMLASSSEYRH 390

  Fly   363 GHAVFFDFLGLFFVTYTENTGIILNYCFAVASVFLVGFSLWR-----MSCVSEVSAGRISILFAS 422
            |..||||.|||..:.|....|.|:||...:|.|..:|..|.|     .:.|.:...|
  Rat   391 GSMVFFDVLGLLVIAYPSRVGSIINYMVVMAVVLYLGRKLLRPKHRNSNYVRDFLCG-------- 447

  Fly   423 HLGLHLAGCLLCIGLPLVMSILYDVSDRTMTYYSNNWLVIGLYICPAIIGLVLPSTL----YHSF 483
             ||:........:...|::::...:..:::::|:..::.:.||....:..::|..||    |:..
  Rat   448 -LGITFISWFTSLVTVLIIAVFVSLIGQSLSWYNYFYIAVCLYGTATVAKIILIHTLAKRFYYVN 511

  Fly   484 KSDDKISHPYQMYVG-------LHAHCVVLSILTIALTAIGLRIPYMCMISLFLYILSLLINLLT 541
            .||        :|:|       |..||..|    :||||.|     .|  |.|:..:.:...|||
  Rat   512 ASD--------LYLGELFFDTSLFVHCGFL----VALTAQG-----FC--SAFMSAVWVAFPLLT 557

  Fly   542 TL--------HDRGYYWVLTVQISQLFQYVYFCYLFYIFLVIFFPAMGRNRDSANPDMLIALICA 598
            .|        |.....::....:.....|:|..||.:....:|.|.:||:.....||:::|.|.|
  Rat   558 KLCVYKDFKKHGAKGRFIALYLLGMFIPYLYGLYLIWAVFEMFTPILGRSGSEIPPDVVLASILA 622

  Fly   599 VGTFFALGFVVP---LINMFRWSTYLLICLGVVTFILSMISITGVGFPY-------RPKTSVMRV 653
            |.......:.:.   |:|..:.:...||.:..|||:|   ..:|..|||       :||    ||
  Rat   623 VCVMILSSYFITFIYLVNSTKKTILTLILVCAVTFLL---VCSGAFFPYSSNPDSPKPK----RV 680

  Fly   654 NFLQTRRMFYEYDGSLSVNDSGYY---FDYQDRRALRP----LKDYAVNLTGLTSVDGYCDRYV- 710
            ......|.|:..:||:...|||.:   |||.....:.|    :.|         ::..:|:...
  Rat   681 FLQHVSRTFHNLEGSVVKRDSGIWINGFDYTGMSHVTPHIPEIND---------TIRAHCEENAP 736

  Fly   711 MCGIPCFW---------SSWCRGISSAAWLPRDE-EVTVPGNLELNFLNKTLSKS---GSSARFE 762
            :||.|  |         .:|        :||..| ....|.:..|      :||.   ..|.:..
  Rat   737 LCGFP--WYLPVHFLIRKNW--------YLPAPEISPRNPAHFRL------VSKEKMPWDSIKLT 785

  Fly   763 FELAGPPHMGLYIRPLDGVAVEDWSFIRTMLDQPEKYSPPYQIYFSYGVDSSPFKFHIEFVK-SD 826
            ||..||.||..|:|...|..:..||....:  ........|.:::|:|:.:|.::|.||..: |:
  Rat   786 FEATGPSHMSFYVRTHKGSTLSQWSLGNGI--PVTSRGGDYFVFYSHGLQASAWQFWIEVQQVSE 848

  Fly   827 GQLDGPIFELGVVGHYVNQDFERDETTLRFIADLPDFVYTMEWPSLFMRYIF 878
            .|.:|.: .:.:..||::.:.:|...........||:.:...|.|.:..::|
  Rat   849 EQPEGMV-TVAIAAHYLSGENKRSSQLDALKEKFPDWSFPSAWVSTYSLFVF 899

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30049	NP_725142.3	M28_Fxna_like	71..378	CDD:349872	153/310 (49%)
Ermp1	XP_006231303.1	M28_Fxna_like	99..406	CDD:349872	153/309 (50%)