| Sequence 1: | NP_725141.1 | Gene: | CG30047 / 246414 | FlyBaseID: | FBgn0050047 | Length: | 879 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_003225.2 | Gene: | TFRC / 7037 | HGNCID: | 11763 | Length: | 760 | Species: | Homo sapiens |
| Alignment Length: | 185 | Identity: | 37/185 - (20%) |
|---|---|---|---|
| Similarity: | 72/185 - (38%) | Gaps: | 40/185 - (21%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 103 TTVAFLEEEVENIRAAMRSDLYELQLDVQHPSGAYMHWQMVNMYQGVTNVVVKISSRSSNSSSYL 167
Fly 168 LVNSHFDS-KPSSPGSGDDGTMVVVMLEVLRQVAISD--TPFEHPIVFLFNGAEENPLEASHGFI 229
Fly 230 TQHKW-AGNCKAL-------INLEVAGSGGRDLLFQSGPNNPWLIKYYYQNAKHP 276 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG30047 | NP_725141.1 | M28_Fxna_like | 72..379 | CDD:349872 | 37/185 (20%) |
| TFRC | NP_003225.2 | Mediates interaction with SH3BP4. /evidence=ECO:0000269|PubMed:16325581 | 1..67 | ||
| Endocytosis signal. /evidence=ECO:0000269|PubMed:2298808 | 20..23 | ||||
| Stop-transfer sequence. /evidence=ECO:0000303|PubMed:6090955 | 58..61 | ||||
| PA_TfR | 201..377 | CDD:239043 | 3/15 (20%) | ||
| M28_TfR | 364..610 | CDD:349946 | 36/182 (20%) | ||
| Ligand-binding | 569..760 | ||||
| TFR_dimer | 637..750 | CDD:461238 | |||
| Cell attachment site, required for binding to transferrin | 646..648 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||