Protein Alignment CG30047 and FOLH1

DIOPT Version :10

• Sequence 1: NP_725141.1
• Gene: CG30047 / 246414
• FlyBaseID: FBgn0050047
• Length: 879
• Species: Drosophila melanogaster
• Sequence 2: XP_016872921.1
• Gene: FOLH1 / 2346
• HGNCID: 3788
• Length: 805
• Species: Homo sapiens
• Alignment Length: 295
• Identity: 57/295 - (19%)
• Similarity: 101/295 - (34%)
• Gaps: 74/295 - (25%)

  Fly   641 VGFPYRAKTSVMRIHFLHVRRIFYEYDGSVSLSDS-------------GYYFDFQDRRLYYPLEN 692
            ||.|   ...|..|.:...:::..:..||.....|             |:..:|..:::...:.:
Human   342 VGLP---SIPVHPIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHS 403

  Fly   693 TS-----VNLTGLASTSSECDKYLMCGVPCFNHR--WC--------------------KTRAKSH 730
            |:     .|:.|....:.|.|:|::.|    .||  |.                    .|..|..
Human   404 TNEVTRIYNVIGTLRGAVEPDRYVILG----GHRDSWVFGGIDPQSGAAVVHEIVRSFGTLKKEG 464

  Fly   731 WLPRE---------QEVAIPGATSLKLLSKAVLDSGKVARFEFEISGPPHMSLYIQ--PLDGVEV 784
            |.||.         :|..:.|:|.....:..:|....||....:.|...:.:|.:.  ||
Human   465 WRPRRTILFASWDAEEFGLLGSTEWAEENSRLLQERGVAYINADSSIEGNYTLRVDCTPL----- 524

  Fly   785 EDWSFIRNM---LDEPDTYSPPYQIFFAYGADNTPLKF----HIDFAKSSGDFSTPTFQLGFAAS 842
             .:|.:.|:   |..||.......::.::...:...:|    .|....|..||.....:||.|:.
Human   525 -MYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPEFSGMPRISKLGSGNDFEVFFQRLGIASG 588

  Fly   843 FVSYDYDRDAAGLKFISDFPDFAHVMEWPTLYERY 877
            ...|..:.:..  || |.:|.:..|.|...|.|::
Human   589 RARYTKNWETN--KF-SGYPLYHSVYETYELVEKF 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30047	NP_725141.1	M28_Fxna_like	72..379	CDD:349872
FOLH1	XP_016872921.1	Zinc_peptidase_like	113..>169	CDD:472712
		PA_GCPII_like	175..401	CDD:239036	10/61 (16%)
		M28_PSMA_like	<409..650	CDD:349942	46/225 (20%)
		TFR_dimer	682..802	CDD:461238