DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30047 and ermp1

DIOPT Version :9

Sequence 1:	NP_725141.1	Gene:	CG30047 / 246414	FlyBaseID:	FBgn0050047	Length:	879	Species:	Drosophila melanogaster
Sequence 2:	XP_005173917.3	Gene:	ermp1 / 101883637	-ID:	-	Length:	886	Species:	Danio rerio

Alignment Length:	905	Identity:	301/905 - (33%)
Similarity:	454/905 - (50%)	Gaps:	101/905 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 VNVLSQQKLRRHRLPWYYAPS-----------FLLLWVALFYAVVYPLYHRLPDSVLISHESSKP 72
            :|.|.:.|||        ||.           .|||.   |..:::.|.|.....::|    ..|
Zfish    35 LNGLRRLKLR--------APGSGPLLTEARAVLLLLG---FVCLLWTLVHLSVQQLII----RSP 84

  Fly    73 GQFVAERAQRLLYKYDKIGPKVVGSVANEVTTVAFLEEEVENIRAAMRSDLYELQLDVQHPSGAY 137
            |.|.|.||::.|.:...:||:.|||..||:.||.:|.|::|.||:..||..:.:.:|||.|:|::
Zfish    85 GTFNALRARKHLDQITSVGPRTVGSPENEILTVNYLLEQIEQIRSESRSGPHSITVDVQKPTGSF 149

  Fly   138 ---MHWQMVNMYQGVTNVVVKISSRSSNSSSYLLVNSHFDSKPSSPGSGDDGTMVVVMLEVLRQV 199
               ......:.|..|||:.||:..:|| :..::|.|.||||..:|||:.||.....||||||..:
Zfish   150 SIDFLGGFTSYYDRVTNIAVKLEPKSS-AQHFMLANCHFDSVANSPGASDDAVSCSVMLEVLHSL 213

  Fly   200 AISDTPFEHPIVFLFNGAEENPLEASHGFITQHKWAGNCKALINLEVAGSGGRDLLFQSGPNNPW 264
            |...||.:|.::|||||||||.|:|||||||||.||...:|.||||.||.||::::||:||.|||
Zfish   214 ANLSTPIKHGVIFLFNGAEENILQASHGFITQHPWAQQVRAFINLEAAGVGGKEVVFQTGPENPW 278

  Fly   265 LIKYYYQNAKHPFATTMAEEIFQSGILPSDTDFRIFRDYGQLPGLDMAQISNGYVYHTIFDNVQA 329
            |::.|.:.|.||||:.:.:|:|||||:||||||||:||:|.:||:|:|.|.||::|||.:|..:.
Zfish   279 LVQAYVRAAVHPFASVVGQEVFQSGIIPSDTDFRIYRDFGNIPGIDLAFIENGFIYHTKYDTPER 343

  Fly   330 VPIDSLQSSGDNALSLVRAFADAPEMQNPEDHSEGHAVFFDYLGLFFVYYTENTGIVLNCCIAVA 394
            :..||:|.:|||.||:::....:.|:.:...:..|:.||||.|||..|.|......::|...|.|
Zfish   344 IHTDSIQRAGDNILSVLQHLVMSDELADSSVYRHGNMVFFDVLGLMVVAYPARVAAIINYLTAAA 408

  Fly   395 SLVLV--VCS------LLRMGRESDVSIG---RVSIWFAIILVLHVLGMILSLGLPLLMAVLFDA 448
            :||.:  .||      .||     ||:..   .|..||..:|.|.::.::|:|           .
Zfish   409 TLVYLSRKCSGGAGVRYLR-----DVACAVCVCVLSWFVTLLTLLIVALLLTL-----------L 457

  Fly   449 GDRSMTYFSNNWLVIGLF----IVPAIIGQILPLTLYYTLKPNDEISHPNHIHMSLHAHCVLLSL 509
            | |||.::::.:..:.|:    ....|:...|...||||     .:|..:...:......:|...
Zfish   458 G-RSMFWYTHFYAAVCLYGSAAAAKIILIHTLAKNLYYT-----GVSAVDLAELFFDVGLLLWCC 516

  Fly   510 IAIILTAISLRTPYLCMMSLLFYGGALLINLLSTLHDRG-----YYWVVLVQVLQLVPFLYFCYL 569
            ..:.||...|.:.|:.||.::|   .||..:|...|.|.     .|.|..:..|. ||:::..:|
Zfish   517 ALVFLTLNGLCSAYVPMMMVVF---PLLSKVLLRTHFRAKGASLQYSVFYLMGLS-VPYVHIMFL 577

  Fly   570 FYTFLLVFFPMLGRFGHGTNPDLLIALICAVGTFFALGFVAPLINIFRWPKLALLGLGVVTFIFS 634
            .:....:|.|:|||.|....||:::|.:..:.......::..|:.:....|..|..||.|..:..
Zfish   578 IWVVFEIFTPILGRSGTEIPPDVVLAALITLAAVILSSYLMHLLYLSCSTKRMLAALGSVFAVMF 642

  Fly   635 MIAVSEVGFPYRAKTS---VMRIHFLHVRRIFYEYDGSVSLSDSGYYFDFQDRRLYYPLENTSVN 696
            ::....:.|||.|..|   ..|:...|..|:|:..||||..||||.:.:..|   |..:::.|.:
Zfish   643 VLVGCGLFFPYSADPSSPRPKRVFVQHTTRVFHALDGSVERSDSGLWINSLD---YTGMQHISAH 704

  Fly   697 LTGL-ASTSSECDKYL-MCGVPCFNHRWCKTRAKSHWLPREQEVAIPGATSLKLLSKAVLDSGKV 759
            :..| .|..:.|...| .||.|.|..  .|...|..|......|:.......:|||:...:.|.:
Zfish   705 VPQLNDSIRTRCQHTLPYCGFPWFLP--VKFLVKKSWYLPAPAVSPEAPLEFRLLSRQQSEWGTL 767

  Fly   760 ARFEFEISGPPHMSLYIQPLDGVEVEDWSFIRNMLDEPDTY--SPPYQIFFAYGADNTPLKFHID 822
             |..||..||.|||||:.|:.|..:..|||    .|....:  |..|.||:::|.|....:|.::
Zfish   768 -RLSFEAKGPTHMSLYLLPVSGASLIGWSF----GDGTPRFDLSGEYFIFYSHGTDAPAWRFSLE 827

  Fly   823 FAKSSGDFSTPTFQLGFAASFVSYDY----DRDAAGL-KFISDFPDFAHVMEWPTLYERY 877
            ......|.|...   |..|..:|..|    |:.:..| ..|:.|||:|....|.:.|..|
Zfish   828 VQPGVSDASPDE---GLLALAISAHYFSGPDKHSPPLHTLINTFPDWAFPSAWSSTYHMY 884

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30047	NP_725141.1	M28_Fxna_like	72..379	CDD:193497	147/309 (48%)
ermp1	XP_005173917.3	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D152011at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010