DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30043 and TRE2

DIOPT Version :9

Sequence 1:	NP_725143.1	Gene:	CG30043 / 246412	FlyBaseID:	FBgn0050043	Length:	878	Species:	Drosophila melanogaster
Sequence 2:	NP_014899.1	Gene:	TRE2 / 854430	SGDID:	S000005782	Length:	809	Species:	Saccharomyces cerevisiae

Alignment Length:	202	Identity:	35/202 - (17%)
Similarity:	69/202 - (34%)	Gaps:	62/202 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 TGGYVFNDMVNMYQGI---HNVIVKLSSKSSQSESYLLLNSHFDSKPGSPGSGDDGTMVVVMME- 193
            :.||:||:..:..:|:   |:::.:.:.||.....:.....:..|.|...|:..|..:...:.|
Yeast   141 SSGYLFNEKASGSKGMFSQHDILFEYAKKSVDLAKFERDLEYISSMPHGSGTKGDAAIYRYIQES 205

  Fly   194 -------VLRQMS---ISEIPFEHPIVFLFNGAEE----------NPLQASHGFITQHKWAEKCK 238
                   ::::|.   .|..|....|.:..|..|:          ||| :|:|.:::
Yeast   206 FDNNGLKLVKEMGYSVYSNYPGNVSISYYDNKNEKHDLELSKENFNPL-SSNGKLSK-------- 261

  Fly   239 AFINLEVGGSGGRDLLFQSGPNNPWLMKYYRQHAKHPFATTMAEEIFQSGVLPSDSDFRIFRDYG 303
              ::|..||.|               ..|..||.|            .|..:....|:.:...|.
Yeast   262 --VSLIYGGKG---------------TTYDLQHLK------------DSKTIEDGKDYVLLLQYD 297

  Fly   304 NIAGLDI 310
            .:....:
Yeast   298 KLVSQQV 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30043	NP_725143.1	M28_Fxna_like	71..377	CDD:193497	35/202 (17%)
CG30043	NP_725143.1	PMT_2	493..>634	CDD:304453
TRE2	NP_014899.1	PA	249..392	CDD:238300	16/94 (17%)
		M28_PMSA_TfR_like	417..643	CDD:349871
		TFR_dimer	668..799	CDD:398094
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900