DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30043 and APE3

DIOPT Version :9

Sequence 1:	NP_725143.1	Gene:	CG30043 / 246412	FlyBaseID:	FBgn0050043	Length:	878	Species:	Drosophila melanogaster
Sequence 2:	NP_009845.2	Gene:	APE3 / 852589	SGDID:	S000000490	Length:	537	Species:	Saccharomyces cerevisiae

Alignment Length:	238	Identity:	53/238 - (22%)
Similarity:	97/238 - (40%)	Gaps:	41/238 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   150 NVIVKLSSKSSQSESYLLLNSHFDSKPGSPGSGDDGTMVVVMMEVLRQMSISEIPFEHPIVFLFN 214
            |:|.  .:|....::.:.|.:|.||....||..|||:..:.::.|.:|::..:|  .:.:.|.:.
Yeast   295 NIIA--DTKHGDPDNIVALGAHSDSVEEGPGINDDGSGTISLLNVAKQLTHFKI--NNKVRFAWW 355

  Fly   215 GAEENPLQASHGF---ITQHKWAEKCKAFINLEVGGSGGRDLLFQSGPN--NP--------WLMK 266
            .|||..|..|:.:   :|:.: ..|.:.|::.::..|...:.......|  ||        ..:.
Yeast   356 AAEEEGLLGSNFYAYNLTKEE-NSKIRVFMDYDMMASPNYEYEIYDANNKENPKGSEELKNLYVD 419

  Fly   267 YYRQHAKHPFATTMAEEIFQSGVLPSD--SDFRIFRD----YGNIA-GLDIAQIENGYV----YH 320
            ||:.|  |...|          ::|.|  ||:..|.:    .|.|| |.:...:.||.|    ||
Yeast   420 YYKAH--HLNYT----------LVPFDGRSDYVGFINNGIPAGGIATGAEKNNVNNGKVLDRCYH 472

  Fly   321 TAFDTYENVPGRSIQNSGNNVLALVRAYSNASELYNTESDDSH 363
            ...|...|:...:...:...:...|..|:::.|.:.......|
Yeast   473 QLCDDVSNLSWDAFITNTKLIAHSVATYADSFEGFPKRETQKH 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30043	NP_725143.1	M28_Fxna_like	71..377	CDD:193497	53/238 (22%)
CG30043	NP_725143.1	PMT_2	493..>634	CDD:304453
APE3	NP_009845.2	M28_SGAP_like	78..506	CDD:349873	51/227 (22%)
APE3	NP_009845.2	PA_ScAPY_like	155..284	CDD:239045
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900