Protein Alignment CG30043 and PFF1

DIOPT Version :10

• Sequence 1: NP_725143.1
• Gene: CG30043 / 246412
• FlyBaseID: FBgn0050043
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_009630.3
• Gene: PFF1 / 852366
• SGDID: S000000278
• Length: 976
• Species: Saccharomyces cerevisiae
• Alignment Length: 724
• Identity: 164/724 - (22%)
• Similarity: 283/724 - (39%)
• Gaps: 194/724 - (26%)

  Fly    35 YAPSFLLLWLALFYAIVIPLYYRLPDR--LTISEESHRP----------GEFVAERAQQYLYT-- 85
            |..:.|.|.|.:.|:|:..||....:|  |.:.:|...|          |:.....|..:.||
Yeast    13 YRKTNLSLLLLITYSIITLLYIFDHERYKLNLPKEDEHPEFNDLLETAWGDLQIITASFHPYTSK 77

  Fly    86 -----YDRIGPKVTGSYANEVTTVEFLVNETEKIRAEMRSDLYDLELDVQSPTGGYVFNDMVNM- 144
                 :|.:..:|.     |:|......:.::...:| ||.|:    ..|.|     ||:....
Yeast    78 ENDKVHDYLLKRVL-----EITGNSSFASVSDDKESE-RSILF----QQQDP-----FNESSRFS 127

  Fly   145 ---YQGIHNVIVKLSSKSSQSESYLLLNSHFDSKPGSPGSGDDGTMVVVMMEVLRQMSISEIPFE 206
               |....|::|||..|:.:.|. |||::||||.|...|:.|||..||.::..|: ..|...| .
Yeast   128 RVTYFESSNILVKLEGKNPEEEG-LLLSAHFDSVPTGYGATDDGMGVVSLLANLK-YHIKHRP-N 189

  Fly   207 HPIVFLFNGAEENPLQASHGFITQHKWAEKCKAFINLEVGGSGGRDLLFQSGPNNPWLMKYYRQH 271
            ..::|.||..||..|..:..:. .|.|:...|..||||..|:||:.:||::...:  ..:.|:|.
Yeast   190 RTLIFNFNNNEEFGLLGASTYF-DHSWSNLTKYVINLEGTGAGGKAVLFRTSDTS--TARIYQQS 251

  Fly   272 AK-HPFATTMAEEIFQSGVLPSDSDFRIFRDYGNIAGLDIAQIENGYVYHTAFDTYENVPGRSIQ 335
            .| :||..::.::.|.|..:.|::|::|:.:.| :.|.|:|..:...:|||..|:.:.....|:.
Yeast   252 VKENPFGNSIYQQGFYSRYVRSETDYKIYEENG-MRGWDVAFYKPRNLYHTIKDSIQYTSKASLW 315

  Fly   336 NSGNNVLALVRAYSNASELYNTESDDSHAVFFDFLGLFFVYYTETTGIVVNCVIGVLSLVLVGCS 400
            :..:..|.| .||..::.|  ..:|.:.|.:|||:||.|...:..|....||:..::|.|:.
Yeast   316 HMLHTSLQL-SAYVASNSL--DTADQTPACYFDFIGLKFFVISAKTLFYWNCIFLLVSPVVA--- 374

  Fly   401 VWRMCHQSEEASLPQISIWFLSILGLHVVGFLLCICLPLLMAVLFDAGDRSLTYFTSNWLVFGLY 465
                                   :||:::                 :.|| :|:.:.:|
Yeast   375 -----------------------IGLYLI-----------------SRDR-MTWKSYSW------ 392

  Fly   466 VCPAIIGLVLPLTLYYTLLPNEKLSQAYQLQLSLHAHLVVQALLALILTAMGLRSQYLCLISMIF 530
                         |.:|..|           |||.|.::||.|.:..:    :||..|..
Yeast   393 -------------LSWTRFP-----------LSLAAGIIVQKLFSNDI----IRSNPLTF----- 424

  Fly   531 YGGALLINLVSTLHDRGYYWVPIVMFLQVLPFSYF---CYLFY-------------MFLVIFIPV 579
                          .|.|:|.....|.||:..||.   |..|:             :|::::..:
Yeast   425 --------------SRNYFWPISAFFTQVIFTSYVLINCSNFFFPCADMKSLSIIELFIILWTIL 475

  Fly   580 LGRNGYSTNPDLIVGLLCGVCVFFALGFAAQLINMFRWPKLILLGLGVMTFIFCMIAVSDVGFPY 644
            |..:....:.|.....|..:.:||.|...|.::      :|:.|.||:
Yeast   476 LFTSKLLYSSDYRYTGLYPLSIFFLLSTIAAIL------RLLALALGM----------------- 517

  Fly   645 RAKTNVMR------ANCLHTRRIFYEHDGSVS-RSDSGYYFNYQDRRAFAPLEDSALDLTGLEPV 702
            |.:..:.|      :|.....:|..|.||..: ........:.||.:  |.::|..:..|...|.
Yeast   518 RTRKRLGRECRDHHSNYSSHSQIDMERDGQENLEQPQDQLTSSQDDQ--ASIQDDNVSTTSAGPS 580

  Fly   703 ANRCDDYVM 711
            .|..:|:.|
Yeast   581 HNVDEDHGM 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30043	NP_725143.1	M28_Fxna_like	71..377	CDD:349872	91/327 (28%)
		YfcC	<534..>615	CDD:440899	18/96 (19%)
PFF1	NP_009630.3	M28_Fxna_like	50..354	CDD:349872	91/328 (28%)
		DUF2189	366..>443	CDD:470522	27/173 (16%)