DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30043 and AT5G20660

DIOPT Version :9

Sequence 1:	NP_725143.1	Gene:	CG30043 / 246412	FlyBaseID:	FBgn0050043	Length:	878	Species:	Drosophila melanogaster
Sequence 2:	NP_197566.1	Gene:	AT5G20660 / 832189	AraportID:	AT5G20660	Length:	910	Species:	Arabidopsis thaliana

Alignment Length:	886	Identity:	212/886 - (23%)
Similarity:	382/886 - (43%)	Gaps:	198/886 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 EEKTDKENPIDTELVESLSLRKGYVRRPRLSWYYAPSFLLLWLALFYAIVIPLYY-------RLP 59
            ::..|||...|.:       |.|.|                ||::...|....::       .||
plant    27 KDALDKEVQADVK-------RSGKV----------------WLSVLILITYSSWFVYNYQLGNLP 68

  Fly    60 DRLTISEESHRPGEFVAERAQQYLYTYDRIGPKVTGSYANEVTTVEFLVNETEKIR------AEM 118
            ..||..:...|  .|....|.:::....:.||....|.| .|..:|:::.|.||::      .::
plant    69 KPLTAKQAGKR--GFSEIEAIKHVKALTQFGPHPVSSDA-LVHALEYVLAEVEKVKETAHWEVDV 130

  Fly   119 RSDLYDLELDVQSPTGGYVFNDMVNMYQGIHNVIVKLSSK--SSQSESYLLLNSHFDSKPGSPGS 181
            ..|.::.:..|....|| :|.....:|..|.::::::..|  |...::.:|::||.|:...:.|:
plant   131 NVDFFESKFGVNRLVGG-LFKGKSLVYSDISHIVLRILPKYESDAGDNAILVSSHIDTVFTTGGA 194

  Fly   182 GDDGTMVVVMMEVLRQMSISEIPFEHPIVFLFNGAEENPLQASHGFITQHKWAEKCKAFINLEVG 246
            ||..:.|.||:|:.|..|.|...|::.|:||||..||..|..:|.|||||.|:...:..|:||..
plant   195 GDCSSCVAVMLELARSASQSAHGFKNSIIFLFNTGEEEGLNGAHSFITQHPWSSTVRLAIDLEAM 259

  Fly   247 GSGGRDLLFQSGPNNPWLMKYYRQHAKHPFATTMAEEIFQSGVLPSDSDFRIFRDYGNIAGLDIA 311
            |:||:..:||:|| :||.::.:...||:|....:.:::|.||::.|.:||:::::...::|||.|
plant   260 GTGGKSSIFQAGP-SPWAIENFALAAKYPSGQIIGQDLFTSGIIKSATDFQVYKEVAGLSGLDFA 323

  Fly   312 QIENGYVYHTAFDTYENVPGRSIQNSGNNVLALVRAYSNASELYNTE-------SDDSHAVFFDF 369
            ..:|..||||..|..|.:...|:|:.|.|:||.:...:::|:|...:       |:...||:||.
plant   324 FADNTAVYHTKNDKIELIKPGSLQHLGENMLAFLLRVASSSDLPKDKTLQGEERSNPDSAVYFDV 388

  Fly   370 LGLFFVYYTETTGIVVNCVIGVLSLVLVGCSVWRMCHQSEEASLPQISIWFLSIL--GLHVVGFL 432
            ||.:.:.|.::...::     .:|:::          ||       |.||.||:.  |...|..|
plant   389 LGKYMIVYRQSLATML-----YVSVIM----------QS-------ILIWVLSVFMGGYPAVVSL 431

  Fly   433 LCICLPLLMAVLFDAG------------DRSLTYFTSN-WLVFGLYVCPAIIGLVLPLTLYYTLL 484
            :..||.::::.:|...            ..|...|.|| |:|.||:|.|||:|.:....:.:..|
plant   432 ILSCLSIILSWIFSVAFSVAVAFILPWISSSPVPFASNPWMVVGLFVSPAILGSISGQHVAFIFL 496

  Fly   485 PNEKLSQ-AYQLQLSLH-----AHLVVQALLA-------LILTAMG----LRSQYLCLISMI--- 529
            ..:..:: :.::|:|..     |.|..:..|.       |:|.|:|    |.|.||.|:.::
plant   497 RKKSSNRNSNKMQVSPRLRDNLARLEAERWLFKSGFIQWLVLLALGTYYKLGSTYLALVWLVPPA 561

  Fly   530 -FYGGALLINLVSTLHDRGYYWVPIVMFLQVLPFSYFCYLFYMFLVIFIPVLGRNGYSTNPDLIV 593
             .||  ||...:|.:.      :|..:.|..|..|           :.:|:|..:|....   :.
plant   562 FAYG--LLEATLSPIR------LPKPLKLATLLIS-----------LAVPILVSSGSFIQ---LT 604

  Fly   594 GLLCGVCVFFAL--GFAAQLINMFRWPKLILLGLGVMTFI-----FCMIAVSDVGFPYRAKTNVM 651
            |.:.|:.:.|..  |...:      |....|:.:.:.|||     :.:..:...|    ||.:::
plant   605 GTMIGMLIRFDSNPGVTPE------WLGSALIAVAIATFISLSMVYLLAYIHLSG----AKKSIV 659

  Fly   652 RANCLHTRRIFYEHDGSVSRSDSGYYFNYQDRRAFAPLEDSALDLTGLEPVANRCDDYVMCGIPC 716
            .|.|:.|..       |::...||....:.:..|.|......:|.:|.:.||
plant   660 TALCIITAL-------SLALVSSGVLPAFTEDTARAVNVVHVVDTSGQDQVA------------- 704

  Fly   717 FYYSWCKWRQWDGWLPRESEVILPG-----ELTLDFLGYTVLESGTVARYEFELAGPPH------ 770
             :.|  .:....|.|..|:|.|..|     |..:||:.:.. :...|.:.:.|:....|
plant   705 -FIS--LFSNTPGNLNMEAEQIKEGFRCGRENKIDFVSFEA-KYNCVTKKDAEVGWDKHDIPVLR 765

  Fly   771 ------------MNLFIQPVGSAKVDDWSFVRKMLDEPEEF 799
                        :.:.:...||::   |: :|..:||.|:|
plant   766 VINDKEREGGRVIAVSMDTGGSSR---WT-LRIDMDEIEDF 802

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30043	NP_725143.1	M28_Fxna_like	71..377	CDD:193497	97/320 (30%)
CG30043	NP_725143.1	PMT_2	493..>634	CDD:304453	35/167 (21%)
AT5G20660	NP_197566.1	M28_Fxna_like	78..396	CDD:193497	98/322 (30%)
AT5G20660	NP_197566.1	MFS	510..>594	CDD:304372	23/102 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	161	1.000	Domainoid score	I1255
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D248924at2759
OrthoFinder	1	1.000	-	-		FOG0000591
OrthoInspector	1	1.000	-	-		otm3522
orthoMCL	1	0.900	-	-		OOG6_101747
Panther	1	1.100	-	-	O	PTHR12147
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X435
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.780