Protein Alignment CG30043 and ERMP1

DIOPT Version :10

• Sequence 1: NP_725143.1
• Gene: CG30043 / 246412
• FlyBaseID: FBgn0050043
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_079172.2
• Gene: ERMP1 / 79956
• HGNCID: 23703
• Length: 904
• Species: Homo sapiens
• Alignment Length: 886
• Identity: 276/886 - (31%)
• Similarity: 433/886 - (48%)
• Gaps: 105/886 - (11%)

  Fly    42 LWLALFYAIVIPLYYRLPDRLTISEESHRPGEFVAERAQQYLYTYDRIGPKVTGSYANEVTTVEF 106
            |.|||:...:..|......:|.:...:...|||.|.:|:.||.....|||:.|||..||:.||.:
Human    75 LGLALYLIALRTLVQLSLQQLVLRGAAGHRGEFDALQARDYLEHITSIGPRTTGSPENEILTVHY 139

  Fly   107 LVNETEKIRAEMRSDLYDLELDVQSPTGGY---VFNDMVNMYQGIHNVIVKLSSKSSQSESYLLL 168
            |:.:.:.|..:..| |:.:.:|||.|||.:   ......:.|..|.||:|||..:.. ::..:|.
Human   140 LLEQIKLIEVQSNS-LHKISVDVQRPTGSFSIDFLGGFTSYYDNITNVVVKLEPRDG-AQHAVLA 202

  Fly   169 NSHFDSKPGSPGSGDDGTMVVVMMEVLRQMSISEIPFEHPIVFLFNGAEENPLQASHGFITQHKW 233
            |.||||...|||:.||.....||:||||.:|.|.....|.::|||||||||.|||||||||||.|
Human   203 NCHFDSVANSPGASDDAVSCSVMLEVLRVLSTSSEALHHAVIFLFNGAEENVLQASHGFITQHPW 267

  Fly   234 AEKCKAFINLEVGGSGGRDLLFQSGPNNPWLMKYYRQHAKHPFATTMAEEIFQSGVLPSDSDFRI 298
            |...:||||||..|.||::|:||:||.||||::.|...||||||:.:|:|:||||::|||:||||
Human   268 ASLIRAFINLEAAGVGGKELVFQTGPENPWLVQAYVSAAKHPFASVVAQEVFQSGIIPSDTDFRI 332

  Fly   299 FRDYGNIAGLDIAQIENGYVYHTAFDTYENVPGRSIQNSGNNVLALVRAYSNASELYNTESDDSH 363
            :||:|||.|:|:|.|||||:|||.:||.:.:...|||.:|:|:||::: :...|::....|...|
Human   333 YRDFGNIPGIDLAFIENGYIYHTKYDTADRILTDSIQRAGDNILAVLK-HLATSDMLAAASKYRH 396

  Fly   364 A--VFFDFLGLFFVYYTETTGIVVNCVIGVLSLVL-VGCSVWRMCHQSEEASLPQISIWFLSILG 425
            .  ||||.||||.:.|....|.::|.:: |:.:|| :|....:..|::......     ||..||
Human   397 GNMVFFDVLGLFVIAYPSRIGSIINYMV-VMGVVLYLGKKFLQPKHKTGNYKKD-----FLCGLG 455

  Fly   426 LHVVGFLLCICLPLLMAVLFDAGDRSLTYFTSNWLVFGLYVCPAIIGLVLPLTL----YYTLLPN 486
            :.::.:...:...|::||......:||:::...::...||....:..::|..||    ||.....
Human   456 ITLISWFTSLVTVLIIAVFISLIGQSLSWYNHFYVSVCLYGTATVAKIILIHTLAKRFYYMNASA 520

  Fly   487 EKLSQAYQLQLSLHAHLVVQALLALILTAMGLRSQYLCLISMIFYGGALLINLV--STLHDRGYY 549
            :.|.:.: ..:||..|    ....:.||..||.|.:   ||.::....||..|.  ......|..
Human   521 QYLGEVF-FDISLFVH----CCFLVTLTYQGLCSAF---ISAVWVAFPLLTKLCVHKDFKQHGAQ 577

  Fly   550 WVPIVMFL--QVLPFSYFCYLFYMFLVIFIPVLGRNGYSTNPDLIVGLLCGVCVFFALGFAAQLI 612
            ...|..:|  ..:|:.|..||.:....:|.|:|||:|....||:::..:...|......:....|
Human   578 GKFIAFYLLGMFIPYLYALYLIWAVFEMFTPILGRSGSEIPPDVVLASILAGCTMILSSYFINFI 642

  Fly   613 NMFRWPKLILLGLGVMTFIFCMIAVSDVGFPYR---AKTNVMRANCLHTRRIFYEHDGSVSRSDS 674
            .:.:..|..:|.|.::..|..::..|...|||.   |.....|....|..|.|::.:|:..:.||
Human   643 YLAKSTKKTMLTLTLVCAITFLLVCSGTFFPYSSNPANPKPKRVFLQHMTRTFHDLEGNAVKRDS 707

  Fly   675 GYYFNYQDRRAFAPLEDSALDLTGL-----------EPVANRCDDYV-MCGIPCFYYSWCKW--- 724
            |.:.|             ..|.||:           :.:...|::.. :||.|        |
Human   708 GIWIN-------------GFDYTGISHITPHIPEINDSIRAHCEENAPLCGFP--------WYLP 751

  Fly   725 ------RQWDGWLPR-ESEVILPGELTLDFLGYTVLESGTVARYEFELAGPPHMNLFIQPVGSAK 782
                  :.|  :||. |.....|....|.....|..:|   .:..||..||.||:.:::....:.
Human   752 VHFLIRKNW--YLPAPEVSPRNPPHFRLISKEQTPWDS---IKLTFEATGPSHMSFYVRAHKGST 811

  Fly   783 VDDWSF------VRKMLDEPEEFQPPYQIFHSYGTDNTSLKFFIDM----EKPDGIFDTPTLELA 837
            :..||.      ..|..|        |.:|:|:|...::.:|:|::    |.|:|:.   |:.:|
Human   812 LSQWSLGNGTPVTSKGGD--------YFVFYSHGLQASAWQFWIEVQVSEEHPEGMV---TVAIA 865

  Fly   838 AVGHWVSFEYERDAEAKDFVAAFPDFVHVMEWPSIFKRYIF 878
            |  |::|.|.:|..:.......|||:.....|...:..::|
Human   866 A--HYLSGEDKRSPQLDALKEKFPDWTFPSAWVCTYDLFVF 904

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30043	NP_725143.1	M28_Fxna_like	71..377	CDD:349872	150/310 (48%)
		YfcC	<534..>615	CDD:440899	20/84 (24%)
ERMP1	NP_079172.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..65
		M28_Fxna_like	104..412	CDD:349872	150/310 (48%)