| Sequence 1: | NP_725143.1 | Gene: | CG30043 / 246412 | FlyBaseID: | FBgn0050043 | Length: | 878 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001121620.1 | Gene: | TFRC / 7037 | HGNCID: | 11763 | Length: | 760 | Species: | Homo sapiens |
| Alignment Length: | 257 | Identity: | 48/257 - (18%) |
|---|---|---|---|
| Similarity: | 96/257 - (37%) | Gaps: | 64/257 - (24%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 102 TTVEFLVNETEKIRAEMRSDLYDLE-LDVQSPTGGYVFNDMVNMYQGIHNVIVKLSSKSSQSESY 165
Fly 166 LLLNSHFDSKPGSPGSGDDGTMVVVMMEVLRQMSISEIPFE--HPIVFLFNGAEENPLQASHGFI 228
Fly 229 TQHKWAE--------KCKAFINLEVGGSGGRDLLFQSGPNNPWLMKYYRQHAKHP---------- 275
Fly 276 -FATTMAEEIFQSGVLPSDSDFRIFRDYGNIAGLDIAQIEN-GYVY-HTAFDTY----ENVP 330 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG30043 | NP_725143.1 | M28_Fxna_like | 71..377 | CDD:193497 | 48/257 (19%) |
| PMT_2 | 493..>634 | CDD:304453 | |||
| TFRC | NP_001121620.1 | Mediates interaction with SH3BP4. /evidence=ECO:0000269|PubMed:16325581 | 1..67 | ||
| Endocytosis signal. /evidence=ECO:0000269|PubMed:2298808 | 20..23 | ||||
| Stop-transfer sequence. /evidence=ECO:0000303|PubMed:6090955 | 58..61 | ||||
| PA_TfR | 201..377 | CDD:239043 | 2/15 (13%) | ||
| M28_TfR | 385..610 | CDD:193572 | 45/233 (19%) | ||
| Ligand-binding | 569..760 | 5/13 (38%) | |||
| TFR_dimer | 642..750 | CDD:282153 | |||
| Cell attachment site, required for binding to transferrin | 646..648 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG2234 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.900 | |||||