DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG30043 and Tfr2

DIOPT Version :10

Sequence 1:NP_725143.1 Gene:CG30043 / 246412 FlyBaseID:FBgn0050043 Length:878 Species:Drosophila melanogaster
Sequence 2:NP_056614.3 Gene:Tfr2 / 50765 MGIID:1354956 Length:798 Species:Mus musculus


Alignment Length:381 Identity:81/381 - (21%)
Similarity:146/381 - (38%) Gaps:106/381 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    59 PDRLTISEESHRPGEFVAERAQQYLYTYDRIGPKVTGSYANEVTTVEF-LVNETE---------- 112
            ||....|::.|:||    ..:.|.:|.:..:|   ||    :..|..| ..|:|:          
Mouse   294 PDPSDFSQDPHKPG----LSSHQAVYGHVHLG---TG----DPYTPGFPSFNQTQFPPVESSGLP 347

  Fly   113 KIRAE-MRSDLYDLELDVQSPTG--------GYVFNDMVNMYQG--------IHNVIVKLSS--- 157
            .|.|: :.:|:.|..|  :..||        |::......:..|        .|.|...:|:   
Mouse   348 SIPAQPISADIADQLL--RKLTGPVAPQEWKGHLSGSPYRLGPGPDLRLVVNNHRVSTPISNIFA 410

  Fly   158 ---KSSQSESYLLLNSHFDSKPGSPGSGDDGTMVVVMMEVLRQMS--ISE--IPFEHPIVFLFNG 215
               ..::.:.|:::.:..|:  ..||:........:::|::|..|  :|.  .|....:...::|
Mouse   411 CIEGFAEPDHYVVIGAQRDA--WGPGAAKSAVGTAILLELVRTFSSMVSNGFRPRRSLLFISWDG 473

  Fly   216 AEENPLQASHGFITQHKWAE--------KCKAFINLE--VGGSGG-------------RDLLFQ- 256
            .:       .|.:...:|.|        |...:::|:  |.|.|.             .::|.| 
Mouse   474 GD-------FGSVGATEWLEGYLSVLHLKAVVYVSLDNSVLGDGKFHAKTSPLLVSLIENILKQV 531

  Fly   257 SGPNNPWLMKYYRQHAKHPFATTMAEEIFQSGVLPSDSDFRIFRDYGNIAGLDIAQIENGYVY-- 319
            ..||:.....|.:....||   :...|:.|.  ||.||....|..:..:..::.:.:|:..||  
Mouse   532 DSPNHSGQTLYEQVALTHP---SWDAEVIQP--LPMDSSAYSFTAFAGVPAVEFSFMEDDRVYPF 591

  Fly   320 -HTAFDTYEN----VPGRSIQNSGNNVLALVRAYSN-ASELYNTESDDSHAVFFDF 369
             ||..|||||    :.||        :.|:|:|.:. |.:|....|.| |.:..||
Mouse   592 LHTKEDTYENLHKMLRGR--------LPAVVQAVAQLAGQLLIRLSHD-HLLPLDF 638

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG30043NP_725143.1 M28_Fxna_like 71..377 CDD:349872 77/369 (21%)
YfcC <534..>615 CDD:440899
Tfr2NP_056614.3 Endocytosis signal. /evidence=ECO:0000255 23..26
PA_TfR 206..396 CDD:239043 24/114 (21%)
M28_TfR 404..637 CDD:349946 53/255 (21%)
TFR_dimer 664..788 CDD:461238
Blue background indicates that the domain is not in the aligned region.

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