DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30043 and naalad2

DIOPT Version :9

Sequence 1:	NP_725143.1	Gene:	CG30043 / 246412	FlyBaseID:	FBgn0050043	Length:	878	Species:	Drosophila melanogaster
Sequence 2:	NP_956571.1	Gene:	naalad2 / 393247	ZFINID:	ZDB-GENE-040426-1025	Length:	745	Species:	Danio rerio

Alignment Length:	295	Identity:	62/295 - (21%)
Similarity:	90/295 - (30%)	Gaps:	114/295 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 RIGPKVTGSYA-----------NEVTTVEFLVNETEKIRAEMRSDLYDLELDVQSPTGG----YV 137
            ||||..|..:.           |:||.:   .|....||..:..|.|.:       .||    :|
Zfish   315 RIGPGFTDGFRQNKVRMNIHTNNQVTRI---YNVIGWIRGAVEPDRYII-------LGGHRDAWV 369

  Fly   138 FN--DMVNMYQGIH-NVIV--KLSSKSSQSESYLLLNSHFDSKPGSPGS---GDDGTMVV----- 189
            |.  |.|:....:| ||..  ||..|..:....|:..|....:.|..||   .:|...|:
Zfish   370 FGGIDPVSGAAVVHENVRAAGKLMKKGWRPRRTLIFASWDAEEFGLQGSTEWAEDNARVLQERAV 434

  Fly   190 ------VMMEVLRQMSISEIPFEHPIVFLFNGAEENPLQASHG---FITQHK---WAEKCKAFIN 242
                  ..:|.:..:.:...|..|.:|:.......:|.:...|   :.:.||   |.||.|
Zfish   435 AYINADSAIEGMYTLRVDCTPSLHTLVYDITKKVLSPEEGEEGMSLYESWHKRDNWPEKDK---- 495

  Fly   243 LEVGGSGGRDLLFQSGPNNPWLMKYYRQHAKHPFATTMAEEIFQSGVLPSDSDFRIFRDYGNIAG 307
                               ||:.|                       |.|.|||..:     ...
Zfish   496 -------------------PWISK-----------------------LGSGSDFEAY-----FIR 513

  Fly   308 LDIAQIENGY-------------VYHTAFDTYENV 329
            |.|......|             |||:.::|||.|
Zfish   514 LGITSGRARYTKNRKTERYSSYPVYHSVYETYEIV 548

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30043	NP_725143.1	M28_Fxna_like	71..377	CDD:193497	62/295 (21%)
CG30043	NP_725143.1	PMT_2	493..>634	CDD:304453
naalad2	NP_956571.1	Zinc_peptidase_like	47..>102	CDD:301362
		PA_GCPII_like	108..333	CDD:239036	5/17 (29%)
		M28_PSMA_like	341..581	CDD:193568	54/269 (20%)
		TFR_dimer	618..733	CDD:282153
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900