DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30043 and CG13160

DIOPT Version :9

Sequence 1:	NP_725143.1	Gene:	CG30043 / 246412	FlyBaseID:	FBgn0050043	Length:	878	Species:	Drosophila melanogaster
Sequence 2:	NP_001260918.1	Gene:	CG13160 / 36343	FlyBaseID:	FBgn0033720	Length:	875	Species:	Drosophila melanogaster

Alignment Length:	854	Identity:	446/854 - (52%)
Similarity:	603/854 - (70%)	Gaps:	5/854 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 VRRPRLSWYYAPSFLLLWLALFYAIVIPLYYRLPDRLTISEESHRPGEFVAERAQQYLYTYDRIG 90
            :|..:.|||:||.:||.|:.||:|::.||:..||..:.||||:.:||:|||||||:.|....|:|
  Fly    26 IRCKQYSWYFAPIYLLFWVGLFFAVIYPLFQALPTGIKISEEADKPGQFVAERAQEILLQISRLG 90

  Fly    91 PKVTGSYANEVTTVEFLVNETEKIRAEMRSDLYDLELDVQSPTGGYVFNDMVNMYQGIHNVIVKL 155
            |:|.|...||||.|..|:.|.||:|..:|.|:|::|::||..:|.|:...:.|.|||:.||||:|
  Fly    91 PRVVGDVDNEVTVVNLLLAEIEKVRQVLRDDVYEMEVEVQRASGSYLIKGLTNHYQGVQNVIVRL 155

  Fly   156 SSKSSQSESYLLLNSHFDSKPGSPGSGDDGTMVVVMMEVLRQMSISEIPFEHPIVFLFNGAEENP 220
            |:|||.|.||||:|||:|:||||||:|||..|||||:||||.:::|..||.|||:||||||||.|
  Fly   156 STKSSNSTSYLLVNSHYDTKPGSPGAGDDAAMVVVMLEVLRLVAVSGDPFLHPIIFLFNGAEEQP 220

  Fly   221 LQASHGFITQHKWAEKCKAFINLEVGGSGGRDLLFQSGPNNPWLMKYYRQHAKHPFATTMAEEIF 285
            :|.||||||||:||..|||.:||:..|:||||||||.|||:||||::||..|.||||||.|||:|
  Fly   221 MQGSHGFITQHRWAANCKALLNLDSAGAGGRDLLFQGGPNHPWLMEHYRNSAPHPFATTTAEEMF 285

  Fly   286 QSGVLPSDSDFRIFRDYGNIAGLDIAQIENGYVYHTAFDTYENVPGRSIQNSGNNVLALVRAYSN 350
            ::|::|||:|||||||:|.:.|||:|.:.||:||||.||.|..:...|:||||:|:||||.:.||
  Fly   286 EAGIIPSDTDFRIFRDFGVVPGLDMAGVYNGFVYHTKFDRYAVISLDSLQNSGDNLLALVWSISN 350

  Fly   351 ASELYNTESDDS-HAVFFDFLGLFFVYYTETTGIVVNCVIGVLSLVLVGCSVWRMCHQSEEASLP 414
            |.|:|:||:..: |||||||:|||||:|.|:|.:.:|......:::||..|:|||...:.:....
  Fly   351 AEEMYDTEAHAAGHAVFFDFIGLFFVHYQESTSLALNLFFSFGAILLVCISLWRMSRVTGQTMGT 415

  Fly   415 QISIWFLSILGLHVVGFLLCICLPLLMAVLFDAGDRSLTYFTSNWLVFGLYVCPAIIGLVLPLTL 479
            ...::.|..| |.:.|.||.:..|||||..:|.|:|:||||:::|||.|||:||::||||||:||
  Fly   416 YAGVFGLLFL-LALAGALLAVAFPLLMATFYDWGNRTLTYFSNSWLVIGLYICPSVIGLVLPMTL 479

  Fly   480 YYTLLPNEKLSQAYQLQLSLHAHLVVQALLALILTAMGLRSQYLCLISMIFYGGALLINLVSTLH 544
            |.|.....|:...|.|.:..||:.|:.|:|.|..||:..||.||.|||:|||..||:|||::.||
  Fly   480 YLTHTKCNKIPHTYYLHIVGHANCVLLAILCLGATALKYRSAYLFLISLIFYVAALIINLLTRLH 544

  Fly   545 DRGYYWVPIVMFLQVLPFSYFCYLFYMFLVIFIPVLGRNGYSTNPDLIVGLLCGVCVFFALGFAA 609
            .|||.|..:::..|::||.|..|||:||::|.||:.||.|.|||||:::|.|||.....||.|||
  Fly   545 CRGYLWSLVLIVFQIIPFIYHAYLFHMFILILIPMTGRFGVSTNPDILIGALCGFGTILALSFAA 609

  Fly   610 QLINMFRWPKLILLGLGVMTFIFCMIAVSDVGFPYRAKTNVMRANCLHTRRIFYEHDGSVSRSDS 674
            .|||:||.|..:|.||.::.||||||||||||||||.|||||||:.:...|.|:|::||:|..||
  Fly   610 PLINVFRRPNCMLGGLALVMFIFCMIAVSDVGFPYRPKTNVMRADFMQVHRKFFEYNGSISHEDS 674

  Fly   675 GYYFNYQDRRAFAPLEDSALDLTGLEPVANRCDDYVMCGIPCFYYSWCKWRQWDGWLPRESEVIL 739
            ||||:..||...|||.|. ::||.|..:...||..:||||||  |.:|..|:...||.||..|.|
  Fly   675 GYYFHLGDRNKEAPLRDH-MNLTNLVRLGEDCDSELMCGIPC--YRYCSAREHALWLAREEPVEL 736

  Fly   740 PGELTLDFLGYTVLESGTVARYEFELAGPPHMNLFIQPVGSAKVDDWSFVRKMLDEPEEFQPPYQ 804
            |....|:||..|||..|...||||.|.|||:|.||.:|:...|:..|:|...|||.|..::||.:
  Fly   737 PYPTVLEFLSKTVLSGGYQVRYEFRLTGPPNMGLFFKPLDGVKLLRWTFAPAMLDNPATYRPPLE 801

  Fly   805 IFHSYGTDNTSLKFFIDMEKPDGIFDTPTLELAAVGHWVSFEYERDAEAKDFVAAFPDFVHVMEW 869
            :..:||.|||.::||:::.|.||.|:.|..|:...||:||...:|||.:.:|:|..|||...|||
  Fly   802 VMLTYGIDNTPIEFFVELSKDDGNFNEPVFEMGVSGHYVSPHDKRDALSLEFLATLPDFAFSMEW 866

  Fly   870 PSIFKRYIF 878
            ||.::|:||
  Fly   867 PSSYERHIF 875

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30043	NP_725143.1	M28_Fxna_like	71..377	CDD:193497	187/306 (61%)
CG30043	NP_725143.1	PMT_2	493..>634	CDD:304453	72/140 (51%)
CG13160	NP_001260918.1	M28_Fxna_like	71..378	CDD:193497	187/306 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446886
Domainoid	1	1.000	161	1.000	Domainoid score	I1255
eggNOG	1	0.900	-	-		E1_COG2234
Homologene	1	1.000	-	-		H121891
Inparanoid	1	1.050	212	1.000	Inparanoid score	I1244
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D14040at33392
OrthoFinder	1	1.000	-	-		FOG0000591
OrthoInspector	1	1.000	-	-		otm25001
orthoMCL	1	0.900	-	-		OOG6_101747
Panther	1	1.100	-	-	P	PTHR12147
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X435
	12	11.800