Protein Alignment CG30043 and Tfrc

DIOPT Version :10

• Sequence 1: NP_725143.1
• Gene: CG30043 / 246412
• FlyBaseID: FBgn0050043
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_035768.1
• Gene: Tfrc / 22042
• MGIID: 98822
• Length: 763
• Species: Mus musculus
• Alignment Length: 204
• Identity: 40/204 - (19%)
• Similarity: 76/204 - (37%)
• Gaps: 65/204 - (31%)

  Fly     3 EKTDKENPIDTELVESLSLRKGYVRRPRLSWYYAPSFLLLWLALFYAIVIPLYYRLPDRLTISEE 67
            |:|||...::||.|.:.|         ||.|                         .|..|:..|
Mouse   105 EETDKSETMETEDVPTSS---------RLYW-------------------------ADLKTLLSE 135

  Fly    68 SHRPGEF--VAERAQQYLYTYDRIGPKVTGSYANEVTTVEFLVNETEKIR-AEMRSDLYDLELDV 129
            .....||  ..::..|..||     |:..||..:| :...::.|:..:.: :::..|.:.:::.|
Mouse   136 KLNSIEFADTIKQLSQNTYT-----PREAGSQKDE-SLAYYIENQFHEFKFSKVWRDEHYVKIQV 194

  Fly   130 QSPTGGYVFNDMVNMYQGIHNVIVKLSSKSSQSESYL-----------LLNSHFDSKPG--SPGS 181
            :|..|    .:||.:.|...|:     ......|.|:           |::::|.:|..  ....
Mouse   195 KSSIG----QNMVTIVQSNGNL-----DPVESPEGYVAFSKPTEVSGKLVHANFGTKKDFEELSY 250

  Fly   182 GDDGTMVVV 190
            ..:|::|:|
Mouse   251 SVNGSLVIV 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30043	NP_725143.1	M28_Fxna_like	71..377	CDD:349872	26/136 (19%)
		YfcC	<534..>615	CDD:440899
Tfrc	NP_035768.1	Mediates interaction with SH3BP4. /evidence=ECO:0000250	1..67
		Endocytosis signal	20..23
		Stop-transfer sequence	58..61
		PA_TfR	203..379	CDD:239043	11/62 (18%)
		M28_TfR	387..613	CDD:349946
		Ligand-binding. /evidence=ECO:0000250	572..763
		TFR_dimer	640..753	CDD:461238
		Cell attachment site. /evidence=ECO:0000255	649..651