Protein Alignment CG30043 and C44B7.11

DIOPT Version :10

• Sequence 1: NP_725143.1
• Gene: CG30043 / 246412
• FlyBaseID: FBgn0050043
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_495410.4
• Gene: C44B7.11 / 183431
• WormBaseID: WBGene00016631
• Length: 895
• Species: Caenorhabditis elegans
• Alignment Length: 960
• Identity: 264/960 - (27%)
• Similarity: 424/960 - (44%)
• Gaps: 188/960 - (19%)

  Fly     1 MEEKTDKENPIDTELVESLSLRKGYVRRPRLSWYYAPSFLLLWLALFYAIVIP----LYYRLPDR 61
            :|:::.:.:....|:.:.:||     .|| ..|.:        :.||:.::|.    |:..||:.
 Worm    17 LEKESLQNDETQREMEKDISL-----LRP-AHWNF--------IGLFFLVLIIGTTFLHKCLPEP 67

  Fly    62 LTISEESHRPGEFVAERAQQYLYTYDRIGPKVTGSYANEVTTVEFLVNETEKIRAEMRS-DLYDL 125
            ...::|.   .:|..:||.:.|......|.|..|||..|..|...::.|...||::.:: :....
 Worm    68 KDPNQEE---TQFSEKRAVKVLQELSDYGWKPAGSYNCEELTRNRILKELNDIRSQNQNVENLRF 129

  Fly   126 ELDVQSPTGGYVF--NDMVNM---YQGIHNVIVKLSSKSSQSESYLLLNSHFDSKPGSPGSGDDG 185
            ::|.|..:|.:..  :|...|   |:.:.||:.:|.....:.:..:|||.|:||.|.|....||.
 Worm   130 DIDTQYVSGCFDIPAHDTEGMNICYRNVSNVMARLGKGEKKDKISVLLNCHYDSWPTSNAGSDDL 194

  Fly   186 TMVVVMMEVLRQMSISEIPFEHPIVFLFNGAEENPLQASHGFITQHKWAEKCKAFINLEVGGSGG 250
            :...:|:|::|..|.:.....|.::||||||||:.|.|:|||||||.|..:.:||||||..||||
 Worm   195 SSCALMLELIRLYSKNPHLLNHDVIFLFNGAEESSLLAAHGFITQHSWRHEIRAFINLEASGSGG 259

  Fly   251 RDLLFQSGPNNPWLMKYYRQHAKHPFATTMAEEIFQSGVLPSDSDFRIFRDYGNIAGLDIAQIEN 315
            |:||||:||.|.||:..|.:.|.||..:.:.:|:|||||.|.|:|||||||:|.:.|||:|.::|
 Worm   260 RELLFQAGPANQWLLNSYLEAAIHPHCSVIGQEVFQSGVYPGDTDFRIFRDHGRVPGLDLAFVQN 324

  Fly   316 GYVYHTAFDTYENVPGRSIQNSGNNVLALVRAYSNASELYNT-------ESDDSHAVFFDFLGLF 373
            ||.:||.|||.|.:...|:|.:|.||      ||..:.|..:       |..|...|||||||||
 Worm   325 GYWWHTEFDTAERITKGSLQRAGENV------YSTLNHLLKSPYLEKPAEYADRKTVFFDFLGLF 383

  Fly   374 FVYYTETTGIVVNCVIGVLSLVLVGCSVWR-MCHQSEEASLPQISIWFLSILGLH-VVGFLLCIC 436
            .:.|..:...:||        :|..|:|.. |.|:.       .|..|::.|.|. .|..:|.|.
 Worm   384 VIIYPLSIAHLVN--------MLTICTVIALMSHRF-------YSKTFITFLALRDYVLTILTIA 433

  Fly   437 LPLLMAV----LFDAGDRSLTYFTSNWLVFGLYVCPAI-IGLVLPLTLYYTLLPNEKLSQAYQLQ 496
            | :|.|:    ||..|  :|.::|.:||....|..|:: .|:.:...|...|.|..:......|:
 Worm   434 L-VLKAMTFMSLFTYG--ALRWYTRHWLALVAYGLPSVWAGISVQGLLTARLAPKAREEYGSTLE 495

  Fly   497 LSLHAHLVVQALLALILTAMGLRSQYL-------CLISMIFYGGAL----LINLVSTLHDRGYYW 550
            | :|..|:...|||  .|...:.|.:|       .:.|:|.|.||.    ..|.:.||
 Worm   496 L-IHLTLISGILLA--FTYYDIASGFLFALLLVPAIKSIITYFGAWPTCPTFNTILTL------- 550

  Fly   551 VPIVMFLQVLPF---SYFCYLFYMFLVIFIPVLGRNGYSTNP--DLIVGLLCGVCVFFALG---- 606
                    :|.|   :...|...|.|.||||::||:.|:..|  ...|....| |:..:||
 Worm   551 --------ILSFPGCAMAIYTTEMLLSIFIPIMGRSSYNPEPAVSFFVAFSAG-CIVLSLGGLVA 606

  Fly   607 --------FAAQLINMFRWPKLILLGLGVMTFIFCMIAVSDVGFPYR---AKTNVMRANCLHTRR 660
                    ..|.|:.:.    ..:||:.::|.....:..|....|||   ......|....|..:
 Worm   607 KSRNSRSSNEAGLLELI----YNILGVLLVTLTILYVFSSFWPSPYRFDNVYPTAKRTQFFHVNQ 667

  Fly   661 IFYEHDGSVSRSDSGYYFNYQDRRAFAPLEDSALDLTGLEPVANRCDDYVMCGIPCFYYS--WCK 723
            :.|:.:|.:|.:|:.:|....|.|       .|.|:    |...:..:|.  |:.|.|.:  ||
 Worm   668 MLYDRNGQISVNDTRFYAISHDYR-------GAEDI----PFVKKDPEYT--GLQCHYENNPWC- 718

  Fly   724 WRQWDGWLPRESEVILP--GELT------------------LDFLGYTVLE-------SGTVARY 761
                      |:..:.|  |.|.                  :..||.:...       .|.: .|
 Worm   719 ----------ETPFLFPTKGRLNERNIRVRSVDERLKFKHPVKILGISKRHGVDSKDGKGNI-EY 772

  Fly   762 EFELAGPPHMNLFIQPVGSAKVDDWSFVRKMLDEPEEFQPPYQIFHSYGTDNTSLK--FFIDMEK 824
            .|.:.|...::::|.|..:     |......:.:|:..|....::::..|.|...:  |.:.::|
 Worm   773 SFSVIGTGQISVYIIPDTT-----WLITNTSVTQPKTPQENMFLYYTCSTPNNICEWMFKVTIKK 832

  Fly   825 PDGIFDTPT----LELAAVGHWVSFEYERDAEAKDFVAAFPD-FVHVMEW 869
            ..   .||:    |.:....|::.....:....|:.:|...: .|:..||
 Worm   833 TT---QTPSDDKPLLIGISSHYLHGPEMQSESIKNMIAKIQENRVNSPEW 879

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30043	NP_725143.1	M28_Fxna_like	71..377	CDD:349872	128/318 (40%)
		YfcC	<534..>615	CDD:440899	24/101 (24%)
C44B7.11	NP_495410.4	M28_Fxna_like	75..387	CDD:349872	128/317 (40%)
		COG5373	<444..>646	CDD:444140	55/226 (24%)