Protein Alignment CG30043 and ermp1

DIOPT Version :10

• Sequence 1: NP_725143.1
• Gene: CG30043 / 246412
• FlyBaseID: FBgn0050043
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: XP_004910853.1
• Gene: ermp1 / 100145630
• XenbaseID: XB-GENE-984733
• Length: 876
• Species: Xenopus tropicalis
• Alignment Length: 875
• Identity: 266/875 - (30%)
• Similarity: 436/875 - (49%)
• Gaps: 89/875 - (10%)

  Fly    44 LALFYAIVIPLYYRLPDRLTISEESHRPGEFVAERAQQYLYTYDRIGPKVTGSYANEVTTVEFLV 108
            |.|.|.:.:.....:..|..::...|..| |.|..|::||.....|..::.||..||:..|::|:
 Frog    51 LLLLYVLGVRGLVHISLRQLVTPGGHSTG-FNASTAREYLQQITSIDSRIVGSPENEIIAVDYLL 114

  Fly   109 NETEKIRAEMRSDLYDLELDVQSPTGGY---VFNDMVNMYQGIHNVIVKLSSKSSQSESYLLLNS 170
            .:.:.|..::.| ::.:.:|||.|||.:   ......:.|..|.|:.|||..:.. :|..:|.|.
 Frog   115 GKIKDIEEKVNS-VHKITVDVQRPTGTFSIDFLGGFTSYYDNITNIAVKLEPEFG-AEHAVLANC 177

  Fly   171 HFDSKPGSPGSGDDGTMVVVMMEVLRQMSISEIPFEHPIVFLFNGAEENPLQASHGFITQHKWAE 235
            ||||...:||:.||.....||:|:|..:|:|..|..|.|:|||||||||.||.||||||||.||:
 Frog   178 HFDSVANTPGASDDAVSCAVMLEILGSLSVSSKPLRHAIIFLFNGAEENILQGSHGFITQHPWAK 242

  Fly   236 KCKAFINLEVGGSGGRDLLFQSGPNNPWLMKYYRQHAKHPFATTMAEEIFQSGVLPSDSDFRIFR 300
            ..:||||||..|.||::|:||:||.||||::.|...|.||||:.:|:|:||||::|||:||||:|
 Frog   243 MVRAFINLEAAGVGGKELVFQTGPENPWLVQAYALAAVHPFASVVAQEVFQSGIIPSDTDFRIYR 307

  Fly   301 DYGNIAGLDIAQIENGYVYHTAFDTYENVPGRSIQNSGNNVLALVRAYSNASELYNTESD---DS 362
            |:|||.|:|:|.|||||:|||.:||:..:...|||.:|:|:|.::...:.:|:|  .||.   ..
 Frog   308 DFGNIPGIDLAFIENGYIYHTKYDTWNRILTESIQRAGDNILGVLHYLATSSQL--AESSKFRHG 370

  Fly   363 HAVFFDFLGLFFVYYTETTGIVVNCVIGVLSLVLVGCSVWRMCHQSEEASLPQISIWFLSILGLH 427
            :.||||..|||.:.|....|.::|.:...::|..:|..:.:. .|........:...||    :.
 Frog   371 NMVFFDVCGLFVLSYPARLGTIINYITAAVTLFYIGKKIIKY-KQGGTNYARDLVYGFL----IT 430

  Fly   428 VVGFLLCICLPLLMAVLFDAGDRSLTYFTSNWLVFGLYVCPAIIGLVLPLTLYYTLLPNEKLSQA 492
            :|.::..:...|::|||.....::|.::|..::...||...|:..|:|..:|..|.......||
 Frog   431 LVSWVSALVTVLIIAVLVSLAGKALFWYTHFYVSVFLYGSAAVAKLILVHSLAKTFFFAGASSQ- 494

  Fly   493 YQLQLSLHAHLVVQALLALILTAMGLRSQYLCLISMIFYGGALLINLV---STLHDRGYYWVPIV 554
            |...:.....|::..:..::||..||.|.|.....:||   .||..|:   ..:|....|...::
 Frog   495 YLGDVFFDISLIIWCIPLVLLTQSGLCSAYFFAAWIIF---PLLTKLLLQPDIIHQGSPYKFTVI 556

  Fly   555 MFLQVLPFSYFCYLFYMFLV--IFIPVLGRNGYSTNPDLIVGLLCGVCVFFALGFAAQLINMFRW 617
            ..|.:.| .|...:::::.|  :|.|:|||:|....||:::|.|...|....:.:....|.:.:.
 Frog   557 YLLGLFP-PYLHTMYHVWAVFEMFTPILGRSGTEIPPDVVLGFLIIACTIMLISYFISFIYLVKN 620

  Fly   618 PKLILLGLGVMTFIFCMIAVSDVGFPYRAKTNVMRANCL---HTRRIFYEHDGSVSRSDSGYYFN 679
            .|.|::.|.|::.:..::..|.:.|||.:.|:..:...:   ||.|.|:...|.|.:.|||.:.|
 Frog   621 TKNIIVPLAVLSVLTFLLVCSGMFFPYSSSTDSPKPKRIFLQHTTRTFHSLTGEVVKKDSGIWIN 685

  Fly   680 YQDRRAFAPLEDSALDLTGL-----------EPVANRCDDYVMCGIPCFY--YSWCKWRQWDGWL 731
                         ..|.||:           :.|...|||..:||.|.::  ::..: :.|  :|
 Frog   686 -------------GFDYTGISHVTPHFPELNDTVRAPCDDAPLCGFPWYFPVHNLIR-KNW--YL 734

  Fly   732 PRESEVILPGELTLDFLGYTVLESGTVARYE---------FELAGPPHMNLFIQPVGSAKVDDWS 787
            |.....|           |...|...|:|.|         ||..||.||.::::|...:.:..||
 Frog   735 PAPPAPI-----------YEHTEFKLVSREEMSWGTTRLHFEAKGPSHMTVYVRPHADSVLSSWS 788

  Fly   788 F---VRKMLDEPEEFQPPYQIFHSYGTDNTSLKFFIDMEKPDGIFDTPTLELAAVG-HWVSFEYE 848
            .   :.....|.:     |.||:|:|....:.||:|:::  :...::..:...||| |:...:..
 Frog   789 LGDGIPIASGEKD-----YFIFYSHGLYAPAWKFWIEVK--NSADESKGIVTVAVGSHYFFGDSR 846

  Fly   849 RDAEAKDFVAAFPDFVHVMEWPSIFKRYIF 878
            .....|.....|||:.....|...:..|::
 Frog   847 NSPHLKTVELKFPDWSFPSSWVCTYDLYVY 876

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30043	NP_725143.1	M28_Fxna_like	71..377	CDD:349872	140/311 (45%)
		YfcC	<534..>615	CDD:440899	21/85 (25%)
ermp1	XP_004910853.1	M28_Fxna_like	78..385	CDD:349872	140/311 (45%)