DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG30043 and NAALADL1

DIOPT Version :10

Sequence 1:NP_725143.1 Gene:CG30043 / 246412 FlyBaseID:FBgn0050043 Length:878 Species:Drosophila melanogaster
Sequence 2:NP_005459.2 Gene:NAALADL1 / 10004 HGNCID:23536 Length:740 Species:Homo sapiens


Alignment Length:432 Identity:88/432 - (20%)
Similarity:145/432 - (33%) Gaps:155/432 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly    32 SWYYAPSFLLLWLALFYAIVIPLYYRLPDRLTISEESHRPGEFVAERAQQYLYTYDRIG---PKV 93
            |||..||.:                                    ||...|.|..|.:.   |.|
Human   236 SWYLPPSGV------------------------------------ERGSYYEYFGDPLTPYLPAV 264

  Fly    94 TGSYANEVTTVE-FLVNETEKIRAEMRSDLYDLELDVQS----------------------PTGG 135
            ..|:..::..|. |....|:.|..:   |..||..::..                      |.|.
Human   265 PSSFRVDLANVSGFPPIPTQPIGFQ---DARDLLCNLNGTLAPATWQGALGCHYRLGPGFRPDGD 326

  Fly   136 YVFNDMVNMYQGIHNVIVKLSSKSS---------QSESYLLLNSHFDSKPGSPGSGDDGTMVVVM 191
            :..:..||:  .::|.: :|.:.|:         :.:.|:|..:|.||  ...|:.|..:...|:
Human   327 FPADSQVNV--SVYNRL-ELRNSSNVLGIIRGAVEPDRYVLYGNHRDS--WVHGAVDPSSGTAVL 386

  Fly   192 MEVLRQMSI-----SEIPFEHPIVFLFNGAEENPLQASHGFITQ--HKWAEKCKAFINLEVGGSG 249
            :|:.|.:..     :..| ...|||...||||..|..|..|..:  :|..|:..|:||:::....
Human   387 LELSRVLGTLLKKGTWRP-RRSIVFASWGAEEFGLIGSTEFTEEFFNKLQERTVAYINVDISVFA 450

  Fly   250 GRDLLFQSGP-------------NNP----------WLMKYYRQHAKHPFATTMAEEIFQSGVLP 291
            ...|..|..|             .:|          |:..:.|....:....::       |.|.
Human   451 NATLRVQGTPPVQSVVFSATKEIRSPGPGDLSIYDNWIRYFNRSSPVYGLVPSL-------GSLG 508

  Fly   292 SDSDFRIFRDYGNIAGLDIAQIENGY--------VYHTAFDTYENV-----PGRS-----IQNSG 338
            :.||:..|..:..|:.:|||...:..        .|||||||::.|     ||.|     .:.:|
Human   509 AGSDYAPFVHFLGISSMDIAYTYDRSKTSARIYPTYHTAFDTFDYVDKFLDPGFSSHQAVARTAG 573

  Fly   339 NNVLALVRAYSNASELYNTESDDSHAVFFDFLGLFFVYYTET 380
            :.:|.|..::                    ||.|....|:||
Human   574 SVILRLSDSF--------------------FLPLKVSDYSET 595

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG30043NP_725143.1 M28_Fxna_like 71..377 CDD:349872 80/388 (21%)
YfcC <534..>615 CDD:440899
NAALADL1NP_005459.2 Zinc_peptidase_like 46..>121 CDD:472712
PA_GCPII_like 109..335 CDD:239036 23/137 (17%)
M28_PSMA_like <348..587 CDD:349942 57/268 (21%)
TFR_dimer 616..735 CDD:461238
Blue background indicates that the domain is not in the aligned region.

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