Protein Alignment CG30031 and PRSS22

DIOPT Version :10

• Sequence 1: NP_725035.1
• Gene: CG30031 / 246404
• FlyBaseID: FBgn0050031
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: XP_054169579.1
• Gene: PRSS22 / 64063
• HGNCID: 14368
• Length: 425
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 96/272 - (35%)
• Similarity: 135/272 - (49%)
• Gaps: 48/272 - (17%)

  Fly    17 GTVPEGLL-------------PQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNVIVT 68
            |:.|..:|             ||...|:|||..:|.|.:||.:|:|::|:|.|.||:.:|..::|
Human   131 GSSPPAILNAARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLLTSRWVIT 195

  Fly    69 AAHC---------LQSVSASVLQIRAGSSYWSSGGVTF----SVSSFKNHEGYNANTMVNDIAII 120
            ||||         |.||.....|:....|.....||.:    .|.|:|  ||..|     |||::
Human   196 AAHCFKDNLNKPYLFSVLLGAWQLGNPGSRSQKVGVAWVEPHPVYSWK--EGACA-----DIALV 253

  Fly   121 KINGALTFSSTIKAIGLASSN---PANGAAASVSGWGTLSYG-SSSIPSQLQYVNVNIVSQSQCA 181
            ::..::.||..:..|.|..::   |.| ....:||||::..| ....|..||.:.|.|:....|
Human   254 RLERSIQFSERVLPICLPDASIHLPPN-THCWISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVC- 316

  Fly   182 SSTYGYGS---QIRSTMICAA--ASGKDACQGDSGGPL---VSGG-VLVGVVSWGYGCAYSNYPG 237
            |..|..|:   .|...|:||.  ...:|||.|||||||   |.|. :|.|::|||.|||..|.||
Human   317 SHLYWRGAGQGPITEDMLCAGYLEGERDACLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNRPG 381

  Fly   238 VYADVAALRSWV 249
            ||..::|.||||
Human   382 VYISLSAHRSWV 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30031	NP_725035.1	Tryp_SPc	30..249	CDD:214473	89/244 (36%)
PRSS22	XP_054169579.1	Tryp_SPc	158..396	CDD:238113	90/245 (37%)