DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30031 and Klk4

DIOPT Version :9

Sequence 1:	NP_725035.1	Gene:	CG30031 / 246404	FlyBaseID:	FBgn0050031	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_064312.1	Gene:	Klk4 / 56640	MGIID:	1861379	Length:	255	Species:	Mus musculus

Alignment Length:	226	Identity:	72/226 - (31%)
Similarity:	106/226 - (46%)	Gaps:	8/226 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 LDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNVIVTAAHCLQSVSASVLQIRAGSSYWS 91
            :..||:.|...:..|.|||.:|.......|.|.:.....:::||||||......|.:........
Mouse    28 VSSRIIQGQDCSPHSQPWQAALFSEDGFFCSGVLVHPQWVLSAAHCLQESYIVGLGLHNLKGSQE 92

  Fly    92 SGGVTFSVSSFKNHEGYNANTMVNDIAIIKINGALTFSSTIKAIGLASSNPANGAAASVSGWGTL 156
            .|...........|..:|..:..||:.:||:|.::..|:||::|.:|:..|..|....|||||.|
Mouse    93 PGSRMLEAHLSIQHPNFNDPSFANDLMLIKLNESVIESNTIRSIPVATQCPTPGDTCLVSGWGQL 157

  Fly   157 SYGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRSTMICAAA--SGKDACQGDSGGPLVSGGV 219
            ..|  .:||.||.||:::.|:..|...   |......:|.||..  ..||:|.||||||:|....
Mouse   158 KNG--KLPSLLQCVNLSVASEETCRLL---YDPVYHLSMFCAGGGQDQKDSCNGDSGGPIVCNRS 217

  Fly   220 LVGVVSWGYG-CAYSNYPGVYADVAALRSWV 249
            |.|:||.|.| |.....|.||.::....:|:
Mouse   218 LQGLVSMGQGKCGQPGIPSVYTNLCKFTNWI 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30031	NP_725035.1	Tryp_SPc	30..249	CDD:214473	71/221 (32%)
Klk4	NP_064312.1	Tryp_SPc	32..251	CDD:238113	71/222 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	156	1.000	Domainoid score	I4174
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910