Protein Alignment CG30031 and PRSS2

DIOPT Version :10

• Sequence 1: NP_725035.1
• Gene: CG30031 / 246404
• FlyBaseID: FBgn0050031
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 100/264 - (37%)
• Similarity: 144/264 - (54%)
• Gaps: 27/264 - (10%)

  Fly     2 LKFVILLSAVACALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNVI 66
            :..:::|:.||.|:.....:      |.:||||.....:|.|:|:|| .||.|.||||:.|...:
Human     1 MNLLLILTFVAAAVAAPFDD------DDKIVGGYICEENSVPYQVSL-NSGYHFCGGSLISEQWV 58

  Fly    67 VTAAHCLQSVSASVL----------QIRAGSSYWS--SGGVTF-SVSSFKNHEGYNANTMVNDIA 118
            |:|.||.:|...|.|          |:|.|.....  .|...| :.:....|..||:.|:.|||.
Human    59 VSAGHCYKSAINSKLSGRGCEYHRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDIL 123

  Fly   119 IIKINGALTFSSTIKAIGLASSNPANGAAASVSGWG-TLSYGSSSIPSQLQYVNVNIVSQSQCAS 182
            :||::.....:|.:.||.|.::.||.|..:.:|||| |||.| :..|.:||.::..::||::|.:
Human   124 LIKLSSPAVINSRVSAISLPTAPPAAGTESLISGWGNTLSSG-ADYPDELQCLDAPVLSQAECEA 187

  Fly   183 STYGYGSQIRSTMICAA--ASGKDACQGDSGGPLVSGGVLVGVVSWGYGCAYSNYPGVYADVAAL 245
            |   |..:|.:.|.|..  ..|||:||||||||:||.|.|.|:||||||||..|.||||..|...
Human   188 S---YPGKITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYGCAQKNRPGVYTKVYNY 249

  Fly   246 RSWV 249
            ..|:
Human   250 VDWI 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30031	NP_725035.1	Tryp_SPc	30..249	CDD:214473	94/234 (40%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	95/235 (40%)