DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30031 and Prss53

DIOPT Version :9

Sequence 1:	NP_725035.1	Gene:	CG30031 / 246404	FlyBaseID:	FBgn0050031	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_006230384.1	Gene:	Prss53 / 499270	RGDID:	1566127	Length:	591	Species:	Rattus norvegicus

Alignment Length:	303	Identity:	72/303 - (23%)
Similarity:	125/303 - (41%)	Gaps:	87/303 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 ACALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNVIVTAAHCLQSV 76
            ||...|..|..  || :|..:.|      .:|||.|::|.|.|.|.||:.:...::|||||.:.:
  Rat    27 ACGQRGPGPPE--PQ-EGNTLPG------EWPWQASVRRQGVHICSGSLVADTWVLTAAHCFEKM 82

  Fly    77 SASVLQIRAGSSYW------------SSGGVTFSVSSFKNHEGYNANTMVNDIAIIKINGALTFS 129
            :.:.|      |.|            |.|.....|::.:..:.||..:..:|:|::::...:..:
  Rat    83 ATAEL------SSWSVVLGSLKQEGLSPGAEEVGVAALQLPKAYNHYSQGSDLALLQLTHPIVHT 141

  Fly   130 STIKAIGLASSNPAN----GAAASVSGW--------------------GTL-------SYGSSSI 163
            :      |....|.:    ||:...:||                    |::       |:..|.:
  Rat   142 T------LCLPQPTHHFPFGASCWATGWDQNTSDGKYCPRHKSRESQTGSVLTVLALCSHCVSEL 200

  Fly   164 PS---------QLQYVNVNIVSQSQCASSTYG------YGSQIRSTMICAAASG--KDACQGDSG 211
            .|         .|:.:.:.::|:..| :..|.      ..:..||.|:|..|..  :..||||||
  Rat   201 DSTLSPLPVSRTLRNLRLRLISRPTC-NCLYNRLHQRLLANPARSGMLCGGAQPGVQGPCQGDSG 264

  Fly   212 GPLV-----SGGVLVGVVSWGYGCAYSNYPGVYADVAALRSWV 249
            ||::     ...|.||::|:...||..:.|.:..|:||..||:
  Rat   265 GPVMCREPDGHWVQVGIISFTSNCAQEDTPVLLTDMAAHSSWL 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30031	NP_725035.1	Tryp_SPc	30..249	CDD:214473	64/283 (23%)
Prss53	XP_006230384.1	Tryp_SPc	45..310	CDD:238113	65/282 (23%)
Prss53	XP_006230384.1	Tryp_SPc	341..561	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343316
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.030