Protein Alignment CG30031 and KLK12

DIOPT Version :9

• Sequence 1: NP_725035.1
• Gene: CG30031 / 246404
• FlyBaseID: FBgn0050031
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 262
• Identity: 88/262 - (33%)
• Similarity: 126/262 - (48%)
• Gaps: 57/262 - (21%)

  Fly     2 LKFVILLSAVACALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNVI 66
            |...:||    |.||  :.:...|    :|..|:....:|.|||:.|....|..|||.:.....:
Human     3 LSIFLLL----CVLG--LSQAATP----KIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWV 57

  Fly    67 VTAAHCLQSVSASVLQIRAGSSYW------------------SSGGVTFSVSSFKNHEGY-NANT 112
            :|||||            :||.||                  .||   |||:    |.|| .|:|
Human    58 LTAAHC------------SGSRYWVRLGEHSLSQLDWTEQIRHSG---FSVT----HPGYLGAST 103

  Fly   113 M-VNDIAIIKINGALTFSSTIKAIGLASSNPANGAAASVSGWGTLSYGSSSIPSQLQYVNVNIVS 176
            . .:|:.::::...:..:|:::.:.|.:.....|....|||||..::..:..|..||.:|::|||
Human   104 SHEHDLRLLRLRLPVRVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVS 168

  Fly   177 QSQCASSTYG-YGSQIRSTMICA-AASGKDACQGDSGGPLVSGGVLVGVVSWGY--GCAYSNYPG 237
            .:.|    :| |..:|.|.|:|| ...|:||||||||||||.||||.|:||||.  .|.....||
Human   169 HATC----HGVYPGRITSNMVCAGGVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPG 229

  Fly   238 VY 239
            ||
Human   230 VY 231

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30031	NP_725035.1	Tryp_SPc	30..249	CDD:214473	81/234 (35%)
KLK12	NP_062544.1	Tryp_SPc	21..236	CDD:214473	81/234 (35%)
		Tryp_SPc	22..236	CDD:238113	81/233 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910