DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG30031 and KLK1

DIOPT Version :9

Sequence 1:NP_725035.1 Gene:CG30031 / 246404 FlyBaseID:FBgn0050031 Length:253 Species:Drosophila melanogaster
Sequence 2:NP_002248.1 Gene:KLK1 / 3816 HGNCID:6357 Length:262 Species:Homo sapiens


Alignment Length:263 Identity:80/263 - (30%)
Similarity:123/263 - (46%) Gaps:28/263 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 FVILLSAVACALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNVIVT 68
            |::|  .:|.:||||   |..|.:..|||||......|.|||.:|....:..|||.:.....::|
Human     3 FLVL--CLALSLGGT---GAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLT 62

  Fly    69 AAHCLQS------------VSASVLQ-IRAGSSYWSSGGVTFSVSSFKNHEGYNANTMVNDIAII 120
            ||||:..            ...:..| :....|:...|   |::|..:||.........:|:.::
Human    63 AAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPG---FNMSLLENHTRQADEDYSHDLMLL 124

  Fly   121 KI-NGALTFSSTIKAIGLASSNPANGAAASVSGWGTLSYGSSSIPSQLQYVNVNIVSQSQCASST 184
            :: ..|.|.:..:|.:.|.:..|..|:....||||::...:.|.|..||.|::.|:...:|..: 
Human   125 RLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKA- 188

  Fly   185 YGYGSQIRSTMICAA--ASGKDACQGDSGGPLVSGGVLVGVVSWGY-GCAYSNYPGVYADVAALR 246
              :..::...|:|..  ..|||.|.|||||||:..|||.||.|||| .|...|.|.|...|.:..
Human   189 --HVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYV 251

  Fly   247 SWV 249
            .|:
Human   252 KWI 254

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG30031NP_725035.1 Tryp_SPc 30..249 CDD:214473 70/235 (30%)
KLK1NP_002248.1 Tryp_SPc 25..257 CDD:238113 70/236 (30%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - mtm8473
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X21
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.910

Return to query results.
Submit another query.