DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG30031 and PRSS53

DIOPT Version :9

Sequence 1:NP_725035.1 Gene:CG30031 / 246404 FlyBaseID:FBgn0050031 Length:253 Species:Drosophila melanogaster
Sequence 2:XP_011544118.1 Gene:PRSS53 / 339105 HGNCID:34407 Length:623 Species:Homo sapiens


Alignment Length:309 Identity:73/309 - (23%)
Similarity:119/309 - (38%) Gaps:81/309 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 LSAVACALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNVIVTAAHC 72
            |.|...|.|...|....|| :|..|.|      .:|||.|::|.|:|.|.||:.:...::|||||
Human    21 LQAAQRACGQRGPGPPKPQ-EGNTVPG------EWPWQASVRRQGAHICSGSLVADTWVLTAAHC 78

  Fly    73 LQSVSASVL---QIRAGS---SYWSSGGVTFSVSSFKNHEGYNANTMVNDIAIIKINGALTFSST 131
            .:..:|:.|   .:..||   ...|.|.....|::.:....||..:..:|:|::::....|.:. 
Human    79 FEKAAATELNSWSVVLGSLQREGLSPGAEEVGVAALQLPRAYNHYSQGSDLALLQLAHPTTHTP- 142

  Fly   132 IKAIGLASSNPAN----GAAASVSGWG----------TLSYGS---------------------- 160
                 |....||:    ||:...:||.          .|..|.                      
Human   143 -----LCLPQPAHRFPFGASCWATGWDQDTSDGKCWPRLKLGEALCLPSVTVSAPNCPGFQSPLL 202

  Fly   161 ------------SSIPSQLQYVNVNIVSQSQCASSTYG------YGSQIRSTMICAAASG--KDA 205
                        |..|..|:.:.:.::|:..| :..|.      ..:..|..|:|.....  :..
Human   203 PRSQTLAPAPSLSPAPGTLRNLRLRLISRPTC-NCIYNQLHQRHLSNPARPGMLCGGPQPGVQGP 266

  Fly   206 CQGDSGGPLV-----SGGVLVGVVSWGYGCAYSNYPGVYADVAALRSWV 249
            ||||||||::     ...|..|::|:...||..:.|.:..:.||..||:
Human   267 CQGDSGGPVLCLEPDGHWVQAGIISFASSCAQEDAPVLLTNTAAHSSWL 315

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG30031NP_725035.1 Tryp_SPc 30..249 CDD:214473 64/285 (22%)
PRSS53XP_011544118.1 Tryp_SPc 42..316 CDD:238113 65/287 (23%)
Tryp_SPc 43..314 CDD:214473 63/283 (22%)
Tryp_SPc 359..>512 CDD:304450
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165149438
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24276
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
22.030

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