DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30031 and TPSG1

DIOPT Version :9

Sequence 1:	NP_725035.1	Gene:	CG30031 / 246404	FlyBaseID:	FBgn0050031	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_011520748.1	Gene:	TPSG1 / 25823	HGNCID:	14134	Length:	346	Species:	Homo sapiens

Alignment Length:	243	Identity:	90/243 - (37%)
Similarity:	121/243 - (49%)	Gaps:	24/243 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 PQLD---GRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNVIVTAAHCLQ-SVSASVLQIRA 85
            ||:.   ||||||.|....::|||.||:....|.||||:.|...::|||||.. |:::|..|:..
Human    54 PQVSDAGGRIVGGHAAPAGAWPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFSGSLNSSDYQVHL 118

  Fly    86 G------SSYWSSGGVTFSVSSFKNHEGYNANTMVNDIAIIKINGALTFSSTIKAIGL--ASSNP 142
            |      |.::|:.......||.....|.:     .|||:::::..:|.||.|..:.|  ||.:.
Human   119 GELEITLSPHFSTVRQIILHSSPSGQPGTS-----GDIALVELSVPVTLSSRILPVCLPEASDDF 178

  Fly   143 ANGAAASVSGWGTLSYGSS-SIPSQLQYVNVNIVSQSQCASSTYGYGSQI-RSTMICAAASGKDA 205
            ..|....|:|||....|.. ..|..|:.|.|::|....|.....|.|..| :..|:||...| ||
Human   179 CPGIRCWVTGWGYTREGEPLPPPYSLREVKVSVVDTETCRRDYPGPGGSILQPDMLCARGPG-DA 242

  Fly   206 CQGDSGGPLV----SGGVLVGVVSWGYGCAYSNYPGVYADVAALRSWV 249
            ||.|||||||    ...|..|.||||.||...|.||||..|.|..:|:
Human   243 CQDDSGGPLVCQVNGAWVQAGTVSWGEGCGRPNRPGVYTRVPAYVNWI 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30031	NP_725035.1	Tryp_SPc	30..249	CDD:214473	86/233 (37%)
TPSG1	XP_011520748.1	Tryp_SPc	62..290	CDD:214473	86/233 (37%)
TPSG1	XP_011520748.1	Tryp_SPc	63..293	CDD:238113	86/234 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I4288
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.960