Protein Alignment CG30031 and KLK11

DIOPT Version :10

• Sequence 1: NP_725035.1
• Gene: CG30031 / 246404
• FlyBaseID: FBgn0050031
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Alignment Length: 278
• Identity: 83/278 - (29%)
• Similarity: 129/278 - (46%)
• Gaps: 48/278 - (17%)

  Fly     5 VILLSAVACALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNVIVTA 69
            :|||:.....:||          :.||:.|......|.|||.:|.......||.::.:...::||
Human    38 LILLALATGLVGG----------ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTA 92

  Fly    70 AHCLQS-VSAS----VLQIRAGSSYWSSGGVTFSV--------------------SSFKNHEGYN 109
            ||||:. ||.:    |....:.|:|..|....:.|                    .||. |.|:|
Human    93 AHCLKPWVSLTSPTHVSPDLSSSNYCLSHLSRYIVHLGQHNLQKEEGCEQTRTATESFP-HPGFN 156

  Fly   110 ANTMV-----NDIAIIKINGALTFSSTIKAIGLASSNPANGAAASVSGWGTLSYGSSSIPSQLQY 169
             |::.     |||.::|:...::.:..::.:.|:|.....|.:..:||||:.|.....:|..|:.
Human   157 -NSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRC 220

  Fly   170 VNVNIVSQSQCASSTYGYGSQIRSTMICAAA--SGKDACQGDSGGPLVSGGVLVGVVSWGYG-CA 231
            .|:.|:...:|.::   |...|..||:||:.  .|||:||||||||||....|.|::|||.. ||
Human   221 ANITIIEHQKCENA---YPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCA 282

  Fly   232 YSNYPGVYADVAALRSWV 249
            .:..||||..|.....|:
Human   283 ITRKPGVYTKVCKYVDWI 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30031	NP_725035.1	Tryp_SPc	30..249	CDD:214473	77/251 (31%)
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	77/251 (31%)