Protein Alignment CG30025 and PRSS27

DIOPT Version :10

• Sequence 1: NP_725036.1
• Gene: CG30025 / 246398
• FlyBaseID: FBgn0050025
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: NP_114154.1
• Gene: PRSS27 / 83886
• HGNCID: 15475
• Length: 290
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 86/270 - (31%)
• Similarity: 135/270 - (50%)
• Gaps: 48/270 - (17%)

  Fly     9 SAVACALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNVIVTAAHCL 73
            :|.||.         .|::..|:|||..|....:|||:|:||:|||.||||:.:...::|||||.
Human    22 AATACG---------RPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCF 77

  Fly    74 QSVS-ASVLQIRAGSSYWSSGG---VTFSVSSFKNHEGYNANTMVNDIAIIKINGALTFSSTIKA 134
            ::.| .|:.|:..|:......|   :...|...:::..|.......|:|::::...:.|::.|..
Human    78 RNTSETSLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILP 142

  Fly   135 IGLASSNPA----NGAAASVSGWGTLSYGSSSIPSQ---------LQYVNVNIVSQSQC-----A 181
            :.|  .:|:    .|....|:|||:        ||:         ||.:.|.|:...:|     .
Human   143 VCL--PDPSVIFETGMNCWVTGWGS--------PSEEDLLPEPRILQKLAVPIIDTPKCNLLYSK 197

  Fly   182 SSTYGYGSQ-IRSTMICAA--ASGKDACQGDSGGPLV----SGGVLVGVVSWGYGCAYSNYPGVY 239
            .:.:||..: |::.|:||.  ...||||:||||||||    ...:..||:|||.|||..|.||||
Human   198 DTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPGVY 262

  Fly   240 ADVAALRSWV 249
            ..|.|..:|:
Human   263 IRVTAHHNWI 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30025	NP_725036.1	Tryp_SPc	30..249	CDD:214473	81/247 (33%)
PRSS27	NP_114154.1	Tryp_SPc	36..275	CDD:238113	81/247 (33%)