DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG30025 and AZU1

DIOPT Version :9

Sequence 1:NP_725036.1 Gene:CG30025 / 246398 FlyBaseID:FBgn0050025 Length:253 Species:Drosophila melanogaster
Sequence 2:NP_001691.1 Gene:AZU1 / 566 HGNCID:913 Length:251 Species:Homo sapiens


Alignment Length:266 Identity:80/266 - (30%)
Similarity:119/266 - (44%) Gaps:35/266 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MLKFVILLSAVACALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNV 65
            |.:..:|  |:...|..:...|..|.||  ||||.......||:..|:|..|.|.|||::..:..
Human     1 MTRLTVL--ALLAGLLASSRAGSSPLLD--IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARF 61

  Fly    66 IVTAAHCLQSVSASVLQIRAGS----SYWSSGGVTFSVSSFKNHEGYNANTMVNDIAIIKIN--G 124
            ::|||.|.||.:..|..:..|:    ........|||:||. :..||:....:||:.:::::  .
Human    62 VMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSM-SENGYDPQQNLNDLMLLQLDREA 125

  Fly   125 ALTFSSTIKAIGLASSNPANGAAASVSGWGTLSYGS--SSIPSQLQYVNVNIVSQSQCASSTYGY 187
            .||.|.||..:.|.::....|....|:|||:...|.  |..|   ::|||.:..:.||       
Human   126 NLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFP---RFVNVTVTPEDQC------- 180

  Fly   188 GSQIRSTMICAAASGK--DACQGDSGGPLVSGGVLVGVVSWGYG-CAYSNYPGVYADVAALRSW- 248
                |...:|.....:  ..|.||.|.|||..|:..||.|:..| |...  |..:..||..|.| 
Human   181 ----RPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWI 239

  Fly   249 --VINN 252
              |:||
Human   240 DGVLNN 245

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG30025NP_725036.1 Tryp_SPc 30..249 CDD:214473 69/232 (30%)
Tryp_SPc 31..252 CDD:238113 70/234 (30%)
AZU1NP_001691.1 Tryp_SPc 27..240 CDD:238113 69/229 (30%)
Possesses antibiotic activity. /evidence=ECO:0000269|PubMed:8506327 46..70 9/23 (39%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D469244at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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