Protein Alignment CG30025 and PRSS8

DIOPT Version :10

• Sequence 1: NP_725036.1
• Gene: CG30025 / 246398
• FlyBaseID: FBgn0050025
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: NP_002764.1
• Gene: PRSS8 / 5652
• HGNCID: 9491
• Length: 343
• Species: Homo sapiens
• Alignment Length: 268
• Identity: 93/268 - (34%)
• Similarity: 141/268 - (52%)
• Gaps: 22/268 - (8%)

  Fly     1 MLKFVILLSAVACALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNV 65
            :|.::.||.:...|.|...|.|:.||  .||.|||:.....:|||:|:...|.|.||||:.|...
Human    17 ILLYLGLLRSGTGAEGAEAPCGVAPQ--ARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQW 79

  Fly    66 IVTAAHCLQSV-SASVLQIRAGSSYWSSGGVTFSVSSFKN---HEGYNANTMVNDIAIIKINGAL 126
            :::||||..|. .....:::.|:....|......||:.|:   |..|.......|||:::::..:
Human    80 VLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPI 144

  Fly   127 TFSSTIKAIGLASSNPA--NGAAASVSGWGTLSYGSSSI-PSQLQYVNVNIVSQSQCASSTYGYG 188
            |||..|:.|.|.::|.:  ||...:|:|||.::...|.: |..||.:.|.::|:..| :..|...
Human   145 TFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETC-NCLYNID 208

  Fly   189 SQ------IRSTMICA--AASGKDACQGDSGGPL---VSG-GVLVGVVSWGYGCAYSNYPGVYAD 241
            ::      ::..|:||  ...|||||||||||||   |.| ..|.|:||||..|...|.||||..
Human   209 AKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTL 273

  Fly   242 VAALRSWV 249
            .::..||:
Human   274 ASSYASWI 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30025	NP_725036.1	Tryp_SPc	30..249	CDD:214473	83/237 (35%)
PRSS8	NP_002764.1	Tryp_SPc	45..284	CDD:238113	83/238 (35%)