DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30025 and prss27

DIOPT Version :9

Sequence 1:	NP_725036.1	Gene:	CG30025 / 246398	FlyBaseID:	FBgn0050025	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_031749235.1	Gene:	prss27 / 496619	XenbaseID:	XB-GENE-5744470	Length:	724	Species:	Xenopus tropicalis

Alignment Length:	275	Identity:	100/275 - (36%)
Similarity:	136/275 - (49%)	Gaps:	34/275 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLKFVILL------SAVACALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGS 59
            ||:.:.||      :|::...|       .|....|||||:......:|||:|:....||.||||
Frog   391 MLRIISLLLAGFAVTAISTGCG-------QPAFSDRIVGGNNAVFGEWPWQVSIVYQNSHICGGS 448

  Fly    60 IYSSNVIVTAAHCL-QSVSASVLQIRAGS---SYWSSGGVTFSVSSFKNHEGYNANTMVNDIAII 120
            :.|||.:|:||||. :|.....:|:..|.   ...:|..|...|.....:..|.......|||::
Frog   449 LVSSNWVVSAAHCFPRSYKIENMQVLLGCFALMNLTSDAVIIRVKRVITYPLYTGEGSSGDIAMV 513

  Fly   121 KINGALTFSSTIKAIGLASSNP--ANGAAASVSGWGTL-SYGSSSIPSQLQYVNVNIVSQSQCAS 182
            ::...:|:||.|..|.:..:|.  .:|....|:|||.: |..|.|.|..||.|.|.:|:.|.| .
Frog   514 EMESPVTYSSYILPICIPLTNEDFPSGKMCWVTGWGNIQSDVSLSPPYPLQEVEVPLVNASSC-D 577

  Fly   183 STYGYGSQ-------IRSTMICAA--ASGKDACQGDSGGPLV--SGG--VLVGVVSWGYGCAYSN 234
            :.|.|.|.       :...||||.  ...||||||||||||.  ||.  .|.|:||||.|||..|
Frog   578 TMYHYNSDLNPATQLVHDDMICAGYPEGQKDACQGDSGGPLACKSGNYWFLTGIVSWGDGCAQPN 642

  Fly   235 YPGVYADVAALRSWV 249
            .||||..|::..||:
Frog   643 RPGVYTKVSSFSSWI 657

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30025	NP_725036.1	Tryp_SPc	30..249	CDD:214473	92/238 (39%)
CG30025	NP_725036.1	Tryp_SPc	31..252	CDD:238113	92/239 (38%)
prss27	XP_031749235.1	Tryp_SPc	34..271	CDD:238113
prss27	XP_031749235.1	Tryp_SPc	420..659	CDD:238113	92/239 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910