Protein Alignment CG30025 and ACR

DIOPT Version :10

• Sequence 1: NP_725036.1
• Gene: CG30025 / 246398
• FlyBaseID: FBgn0050025
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: NP_001088.2
• Gene: ACR / 49
• HGNCID: 126
• Length: 421
• Species: Homo sapiens
• Alignment Length: 294
• Identity: 94/294 - (31%)
• Similarity: 133/294 - (45%)
• Gaps: 57/294 - (19%)

  Fly     1 MLKFVILL----SAVA---CALGGTVPEGLL----PQLDGRIVGGSATTISSFPWQISLQ----- 49
            ||...|||    |.||   ....|  |.||.    ||...|||||.|....::||.:|||
Human     4 MLPTAILLVLAVSVVAKDNATCDG--PCGLRFRQNPQGGVRIVGGKAAQHGAWPWMVSLQIFTYN 66

  Fly    50 RSGSHSCGGSIYSSNVIVTAAHCLQSVSASVLQIRAGSSYWSSGGVTFS-------------VSS 101
            ....|:||||:.:|..::|||||....:    .:......:.:..:|:.             |..
Human    67 SHRYHTCGGSLLNSRWVLTAAHCFVGKN----NVHDWRLVFGAKEITYGNNKPVKAPLQERYVEK 127

  Fly   102 FKNHEGYNANTMVNDIAIIKINGALTFSSTI--------KAIGLASSNPANGAAASVSGWGTLSY 158
            ...||.||:.|..||||:::|...::....|        || ||    |....:..|:|||.:..
Human   128 IIIHEKYNSATEGNDIALVEITPPISCGRFIGPGCLPHFKA-GL----PRGSQSCWVAGWGYIEE 187

  Fly   159 GSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRSTMICAA-ASGK-DACQGDSGGPLV------ 215
            .:....|.|....|:::....| :||..|..:::.|.:||. ..|| |.|||||||||:
Human   188 KAPRPSSILMEARVDLIDLDLC-NSTQWYNGRVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKE 251

  Fly   216 SGGVLVGVVSWGYGCAYSNYPGVYADVAALRSWV 249
            |..|:||:.|||.|||.:..||:|.......:|:
Human   252 SAYVVVGITSWGVGCARAKRPGIYTATWPYLNWI 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30025	NP_725036.1	Tryp_SPc	30..249	CDD:214473	79/252 (31%)
ACR	NP_001088.2	Tryp_SPc	42..285	CDD:214473	79/252 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..316
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..383
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	397..421