Protein Alignment CG30025 and KLK12

DIOPT Version :9

• Sequence 1: NP_725036.1
• Gene: CG30025 / 246398
• FlyBaseID: FBgn0050025
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 92/281 - (32%)
• Similarity: 131/281 - (46%)
• Gaps: 63/281 - (22%)

  Fly     2 LKFVILLSAVACALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNVI 66
            |...:||    |.||  :.:...|    :|..|:....:|.|||:.|....|..|||.:.....:
Human     3 LSIFLLL----CVLG--LSQAATP----KIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWV 57

  Fly    67 VTAAHCLQSVSASVLQIRAGSSYW------------------SSGGVTFSVSSFKNHEGY-NANT 112
            :|||||            :||.||                  .||   |||:    |.|| .|:|
Human    58 LTAAHC------------SGSRYWVRLGEHSLSQLDWTEQIRHSG---FSVT----HPGYLGAST 103

  Fly   113 M-VNDIAIIKINGALTFSSTIKAIGLASSNPANGAAASVSGWGTLSYGSSSIPSQLQYVNVNIVS 176
            . .:|:.::::...:..:|:::.:.|.:.....|....|||||..::..:..|..||.:|::|||
Human   104 SHEHDLRLLRLRLPVRVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVS 168

  Fly   177 QSQCASSTYG-YGSQIRSTMICA-AASGKDACQGDSGGPLVSGGVLVGVVSWGY--GCAYSNYPG 237
            .:.|    :| |..:|.|.|:|| ...|:||||||||||||.||||.|:||||.  .|.....||
Human   169 HATC----HGVYPGRITSNMVCAGGVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPG 229

  Fly   238 VYAD------VAALRSWVINN 252
            ||..      |....||..|:
Human   230 VYTYICNSTLVGLGTSWNFNS 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30025	NP_725036.1	Tryp_SPc	30..249	CDD:214473	83/248 (33%)
		Tryp_SPc	31..252	CDD:238113	84/250 (34%)
KLK12	NP_062544.1	Tryp_SPc	21..236	CDD:214473	81/237 (34%)
		Tryp_SPc	22..236	CDD:238113	81/236 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.920