DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30025 and Tmprss11c

DIOPT Version :9

Sequence 1:	NP_725036.1	Gene:	CG30025 / 246398	FlyBaseID:	FBgn0050025	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_001003979.1	Gene:	Tmprss11c / 408213	RGDID:	1302967	Length:	418	Species:	Rattus norvegicus

Alignment Length:	242	Identity:	86/242 - (35%)
Similarity:	120/242 - (49%)	Gaps:	37/242 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 RIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNVIVTAAHCLQSVSASVLQIR-AGSSYWSSG 93
            ::.||.......:|||.|||::..|.||.::.|::.::|||||.         :| |....|.
  Rat   186 KVAGGQDAEEGEWPWQASLQQNNVHRCGATLISNSWLITAAHCF---------VRSANPKDWK-- 239

  Fly    94 GVTF-----------SVSSFKNHEGYNANTMVNDIAIIKINGALTFSSTIKAIGLASSN---PAN 144
             |:|           :|.|...||.|:.....||||:::::..:.:.:.|:...|..:.   |.|
  Rat   240 -VSFGFLLSKPQAQRAVKSIVIHENYSYPAHNNDIAVVRLSSPVLYENNIRRACLPEATQKFPPN 303

  Fly   145 GAAASVSGWGTLSYGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRSTMICAA-ASGK-DACQ 207
            .... |:|||||.....| |:.||...|.|:....| :|...||..|...|:||. ..|: ||||
  Rat   304 SDVV-VTGWGTLKSDGDS-PNILQKGRVKIIDNKTC-NSGKAYGGVITPGMLCAGFLEGRVDACQ 365

  Fly   208 GDSGGPLV---SGGV--LVGVVSWGYGCAYSNYPGVYADVAALRSWV 249
            ||||||||   |.|:  |.|:||||..||..|.||||..|...|.|:
  Rat   366 GDSGGPLVSEDSKGIWFLAGIVSWGDECALPNKPGVYTRVTHYRDWI 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30025	NP_725036.1	Tryp_SPc	30..249	CDD:214473	85/240 (35%)
CG30025	NP_725036.1	Tryp_SPc	31..252	CDD:238113	86/241 (36%)
Tmprss11c	NP_001003979.1	SEA	62..157	CDD:279699
		Tryp_SPc	186..412	CDD:214473	85/240 (35%)
		Tryp_SPc	187..415	CDD:238113	86/241 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X21
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920