DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30025 and Prss53

DIOPT Version :9

Sequence 1:	NP_725036.1	Gene:	CG30025 / 246398	FlyBaseID:	FBgn0050025	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_001074737.1	Gene:	Prss53 / 330657	MGIID:	2652890	Length:	552	Species:	Mus musculus

Alignment Length:	267	Identity:	70/267 - (26%)
Similarity:	118/267 - (44%)	Gaps:	54/267 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 ACALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNVIVTAAHCLQSV 76
            ||...|..|..  || :|..:.|      .:|||.|::|.|.|.|.||:.:...::|||||.:.:
Mouse    27 ACGQRGPGPPE--PQ-EGNTLPG------EWPWQASVRRQGVHICSGSLVADTWVLTAAHCFEKM 82

  Fly    77 SASVLQIRAGSSYW------------SSGGVTFSVSSFKNHEGYNANTMVNDIAIIKINGALTFS 129
            :.:.|      |.|            |.|.....|::.:..:.||..:..:|:|::::... |..
Mouse    83 ATAEL------SSWSVVLGSLKQEGQSPGAEEVGVAALQLPKAYNHYSQGSDLALLQLTHP-TVQ 140

  Fly   130 STIKAIGLASSNPAN----GAAASVSGWGTLSYGSSSIPSQLQYVNVNIVSQSQCASSTYG---- 186
            :|     |....|..    ||:...:||   ...:|.:...|:.:.:.::|:..| :..|.
Mouse   141 TT-----LCLPQPTYHFPFGASCWATGW---DQNTSDVSRTLRNLRLRLISRPTC-NCLYNRLHQ 196

  Fly   187 --YGSQIRSTMICAAAS-GKDA-CQGDSGGPLV-----SGGVLVGVVSWGYGCAYSNYPGVYADV 242
              ..:..|..|:|..|. |:.. ||||||||::     ...|.||::|:...||..:.|.:..|:
Mouse   197 RLLSNPARPGMLCGGAQPGEQGPCQGDSGGPVMCREPDGHWVQVGIISFTSKCAQEDTPVLLTDM 261

  Fly   243 AALRSWV 249
            |...||:
Mouse   262 AVHSSWL 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30025	NP_725036.1	Tryp_SPc	30..249	CDD:214473	62/247 (25%)
CG30025	NP_725036.1	Tryp_SPc	31..252	CDD:238113	63/248 (25%)
Prss53	NP_001074737.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..46		7/21 (33%)
		Tryp_SPc	45..271	CDD:238113	63/246 (26%)
		Tryp_SPc	311..522	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839498
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030