Protein Alignment CG30025 and TMPRSS12

DIOPT Version :10

• Sequence 1: NP_725036.1
• Gene: CG30025 / 246398
• FlyBaseID: FBgn0050025
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: NP_872365.2
• Gene: TMPRSS12 / 283471
• HGNCID: 28779
• Length: 348
• Species: Homo sapiens
• Alignment Length: 266
• Identity: 76/266 - (28%)
• Similarity: 122/266 - (45%)
• Gaps: 50/266 - (18%)

  Fly    17 GTVPEGLLPQLDG-RIVGGSATTISSFPWQISLQ----RSGSHSCGGSIYSSNVIVTAAHCLQSV 76
            ||.|  |...|.| ||:||:.....::||.:|||    |...|.|||::.....::|||||.:..
Human    65 GTAP--LKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDA 127

  Fly    77 SASVLQIRAGSSYWSSGGVT------------FSVSSFKNHEGYNANTMVNDIAIIKINGALTFS 129
            |..::        |::...|            ..:.:...|..:...:.|||||:..:..|:.::
Human   128 SDPLM--------WTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYN 184

  Fly   130 STIKAIGLASSNPAN-------GAAASVSGWG-TLSYGSSSIPSQLQYVNVNIVSQSQCASSTYG 186
            ..|:.|.|    |.:       .....:|||| |...|:::  :.||...|:.:|:..| :|...
Human   185 DYIQPICL----PFDVFQILDGNTKCFISGWGRTKEEGNAT--NILQDAEVHYISREMC-NSERS 242

  Fly   187 YGSQIRSTMICAA--ASGKDACQGDSGGPLV------SGGVLVGVVSWGYGCAYSNYPGVYADVA 243
            ||..|.:|..||.  ....|.|:|||||||:      ....::|:.|:|:||....:||||...:
Human   243 YGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPS 307

  Fly   244 ALRSWV 249
            ..:.|:
Human   308 FYQKWL 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30025	NP_725036.1	Tryp_SPc	30..249	CDD:214473	69/250 (28%)
TMPRSS12	NP_872365.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..46
		Tryp_SPc	78..316	CDD:238113	69/251 (27%)