Protein Alignment CG30025 and F7

DIOPT Version :10

• Sequence 1: NP_725036.1
• Gene: CG30025 / 246398
• FlyBaseID: FBgn0050025
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: XP_011535776.2
• Gene: F7 / 2155
• HGNCID: 3544
• Length: 495
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 77/283 - (27%)
• Similarity: 119/283 - (42%)
• Gaps: 50/283 - (17%)

  Fly     4 FVILLSAVACALGGTVPEGLLPQLD--------GRIVGGSATTISSFPWQISLQRSGSHSCGGSI 60
            :.:|...|:|......|.|.:|.|:        ||||||........|||:.|..:|:..|||::
Human   207 YSLLADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGGTL 271

  Fly    61 YSSNVIVTAAHCLQSVSASVLQIRAGSSYWSSGGVTFSVSSFKNHEG---------------YNA 110
            .::..:|:||||...:           ..|.:............|:|               |..
Human   272 INTIWVVSAAHCFDKI-----------KNWRNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVP 325

  Fly   111 NTMVNDIAIIKINGALTFSSTIKAIGLASSNPANGAAA-----SVSGWG-TLSYGSSSIPSQLQY 169
            .|..:|||:::::..:..:..:..:.|.....:....|     .||||| .|..|::::  :|..
Human   326 GTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATAL--ELMV 388

  Fly   170 VNVNIVSQSQC--ASSTYGYGSQIRSTMICAAAS--GKDACQGDSGGPLVS----GGVLVGVVSW 226
            :||..:....|  .|...|....|...|.||..|  .||:|:||||||..:    ...|.|:|||
Human   389 LNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSW 453

  Fly   227 GYGCAYSNYPGVYADVAALRSWV 249
            |.|||...:.|||..|:....|:
Human   454 GQGCATVGHFGVYTRVSQYIEWL 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30025	NP_725036.1	Tryp_SPc	30..249	CDD:214473	68/247 (28%)
F7	XP_011535776.2	GLA	36..97	CDD:214503
		EGF_CA	99..135	CDD:238011
		FXa_inhibition	180..216	CDD:464251	2/8 (25%)
		Tryp_SPc	242..478	CDD:238113	68/248 (27%)