Protein Alignment CG30025 and Cfd

DIOPT Version :10

• Sequence 1: NP_725036.1
• Gene: CG30025 / 246398
• FlyBaseID: FBgn0050025
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: NP_038487.1
• Gene: Cfd / 11537
• MGIID: 87931
• Length: 259
• Species: Mus musculus
• Alignment Length: 260
• Identity: 75/260 - (28%)
• Similarity: 126/260 - (48%)
• Gaps: 31/260 - (11%)

  Fly     5 VILLSAVACALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNVIVTA 69
            :::|.|..||          .|..|||:||......:.|:..|:|.:|:|.|||::.....:::|
Mouse    10 LVILGAAVCA----------AQPRGRILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSA 64

  Fly    70 AHCLQSV----SASVL----QIRAGSSY--WSSGGVTFSVSSFKNHEGYNANTMVNDIAIIKING 124
            |||:..|    |..||    .:.|...|  |      :.|.|...|.|...:::.:|:.:.|::.
Mouse    65 AHCMDGVTDDDSVQVLLGAHSLSAPEPYKRW------YDVQSVVPHPGSRPDSLEDDLILFKLSQ 123

  Fly   125 ALTFSSTIKAIGL--ASSNPANGAAASVSGWGTLSYGSSSIPSQLQYVNVNIVSQSQCASSTYGY 187
            ..:....::.:.|  .......|....|:|||.:::.... |..|..:.|:|::::.|...|| :
Mouse   124 NASLGPHVRPLPLQYEDKEVEPGTLCDVAGWGVVTHAGRR-PDVLHQLRVSIMNRTTCNLRTY-H 186

  Fly   188 GSQIRSTMICAAASGKDACQGDSGGPLVSGGVLVGVVSWGYG-CAYSNYPGVYADVAALRSWVIN 251
            ...:...|:||.::.:|.|:||||.|||.|..:.|||:||.. |.....||||..|::.|.|:.|
Mouse   187 DGVVTINMMCAESNRRDTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIEN 251

  Fly   252  251
            Mouse   252  251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30025	NP_725036.1	Tryp_SPc	30..249	CDD:214473	67/231 (29%)
Cfd	NP_038487.1	Tryp_SPc	26..252	CDD:238113	68/234 (29%)
		Self-inhibitor loop. /evidence=ECO:0000250|UniProtKB:P00746	224..228		2/3 (67%)