DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG30025 and tmprss2.12

DIOPT Version :10

Sequence 1:NP_725036.1 Gene:CG30025 / 246398 FlyBaseID:FBgn0050025 Length:253 Species:Drosophila melanogaster
Sequence 2:XP_031752400.1 Gene:tmprss2.12 / 100497514 XenbaseID:XB-GENE-22065925 Length:497 Species:Xenopus tropicalis


Alignment Length:260 Identity:100/260 - (38%)
Similarity:141/260 - (54%) Gaps:28/260 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 VILLSAVACALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSSNVIVTA 69
            |:.|..:.|        ||....:.||||||:.:|..:|||::||...::.||||:.::|.||||
 Frog   243 VVSLKCIDC--------GLSTYGESRIVGGSSASIGDWPWQVNLQYDDTNLCGGSVIAANWIVTA 299

  Fly    70 AHCLQSVSAS-------VLQIRAGSSYWSSGGVTFSVSSFKNHEGYNANTMVNDIAIIKINGALT 127
            |||:|..::|       :.:|:..|.|.||   .:||.....|..|::.|..||||::|:..::.
 Frog   300 AHCVQGDTSSPSLWKAFIGKIKMPSYYDSS---AYSVDRIIVHPDYSSQTNSNDIALMKLKTSIA 361

  Fly   128 FSSTIKAIGLASSNP--ANGAAASVSGWGTLSYGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQ 190
            |||..:.:.|.:...  ..|....:|||||.|. ..||.|.|:|..|.::|.:.| :.|..|...
 Frog   362 FSSISRPVCLPNYGMQWEEGQPCYISGWGTTSQ-KGSISSVLKYAMVPLISPTTC-NQTIMYNGA 424

  Fly   191 IRSTMICAA--ASGKDACQGDSGGPLV----SGGVLVGVVSWGYGCAYSNYPGVYADVAALRSWV 249
            |.|:||||.  ..|.|:||||||||||    |...|||..|||.|||....||||.::.....|:
 Frog   425 ITSSMICAGYPKGGVDSCQGDSGGPLVTKTNSLWWLVGDTSWGDGCANVYRPGVYGNMTVFLQWI 489

  Fly   250  249
             Frog   490  489

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG30025NP_725036.1 Tryp_SPc 30..249 CDD:214473 94/233 (40%)
tmprss2.12XP_031752400.1 LDLa 127..155 CDD:238060
SRCR_2 160..255 CDD:464747 5/19 (26%)
Tryp_SPc 261..489 CDD:238113 93/232 (40%)
Blue background indicates that the domain is not in the aligned region.

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