Protein Alignment sprt and Pard3b

DIOPT Version :9

• Sequence 1: NP_610683.1
• Gene: sprt / 246397
• FlyBaseID: FBgn0082585
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: XP_006496361.1
• Gene: Pard3b / 72823
• MGIID: 1919301
• Length: 1238
• Species: Mus musculus
• Alignment Length: 658
• Identity: 131/658 - (19%)
• Similarity: 220/658 - (33%)
• Gaps: 210/658 - (31%)

  Fly    49 NQETASTTTTSTHCSTTGRRRKGGSLGGTLSSRSTRSESKELRSALQDREAVIQNLRIQLCLGKL 113
            |.:.||.|..:...     |.|.| |.....:|::..|.:|..|..|.:...:..      ||:
Mouse   344 NNDGASRTKAAPPA-----RGKPG-LKAVHLTRASSPEGEEPASPQQSKSPRVPR------LGR- 395

  Fly   114 PRPTGPPLDE-----SEKPAAEQKLNRLKTEAEN---------------KRIKIKNL--KSALEK 156
             :|:.|.|..     |:|.|.:.|:: ||...|.               ..|.:||:  |.|..|
Mouse   396 -KPSSPSLSPLMGFGSKKNAKKIKID-LKKGPEGLGFTVVTRDSSIHGPGPIFVKNILPKGAAVK 458

  Fly   157 ---LDITDNI------DIRIRQAELEYALGRE----ELQMLSIVEEARALQARLEKSKPEAQT-- 206
               |...|.|      |:..|..|...|:.|.    |...|.|..:..:...|..|.:|:...
Mouse   459 DGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETVSLVIARQEGSFLPRELKGEPDCYALS 523

  Fly   207 ------------LYNIISSGVSLSLHAVHATSGRWAVQQRTDQPGFYVEWALEGDGLYK------ 253
                        |.:..|:|:.:||      .|..:.:..||. |.:::..:.|...:|
Mouse   524 LESSEQLTLEIPLNDSGSAGLGVSL------KGNKSRETGTDL-GIFIKSIIHGGAAFKDGRLRM 581

  Fly   254 GDRILEINGRLVTGKSKEELQKQVGNS--------GKCQMVVLRKKSVPIPQKQLDQEKENNMRL 310
            .|:::.:||..:.|||..|..:.:..|        |..|:|:||:     |::.|::..|.....
Mouse   582 NDQLIAVNGETLLGKSNHEAMETLRRSMSMEGNIRGMIQLVILRR-----PERPLEELSECGALS 641

  Fly   311 QHRISYLEEQVRELQTVKEHHPS-------QQQQQQQQQQQNPQQNPQQNPQQTSSNQSQHVTSI 368
            :......:|   .|.|.:.:..|       ...|.:::....|.....:|
Mouse   642 RPGFENCQE---ALSTSRRNDSSILYPFGTYSPQDKRKDLLLPSDGWAEN--------------- 688

  Fly   369 SISSPPSTPPEKPLIF-------------------QRGNYIT----------TLVGGKPIELMGD 404
              ..|||.||...|.:                   |..|:.|          .|...|.::|:.|
Mouse   689 --EVPPSPPPHPALEWGLEDFSHSSGVDSTGYFPDQHVNFRTVTPVRQPELINLKASKSMDLVPD 751

  Fly   405 DMASTQTPPGHVTKTLIKENTHIDLRDRLSHMYSM---PSKSLSASKISINSDSAYMQHHRRDKE 466
            :        |.|.          .|.||.|.....   |:..|..|....:..:|..:..:.|..
Mouse   752 E--------GKVQ----------SLADRRSDSPGKDFGPTLGLKKSSSLESLQTAVAEVRKNDLP 798

  Fly   467 RHRDRQHRERPRDPLQQQQQLHREHLMSTHARSVEHLNHYNGLDRRRDTPRQSESNTLRARLPSD 531
            .||.|.|..|.|...:..:.                     .:|:..|.|.:::::.|..:  |.
Mouse   799 FHRPRPHMVRGRGCNESFRA---------------------AIDKSYDGPEEADADGLSDK--SS 840

  Fly   532 MRSVKSLDFDS-----------ENESKPATETRTTRPTPPKKPLRLSLQRAQSLQTVELHPCADI 585
            .....:|:.:|           ||::|...:|:.......|..|::..::.:     |.|  .|.
Mouse   841 RSGHTALNCESAPQGNPELDNVENKAKNIKKTKEKEKKKGKGKLKVKEKKLK-----EEH--EDA 898

  Fly   586 ERKRPMKR 593
            |||  |||
Mouse   899 ERK--MKR 904

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sprt	NP_610683.1	PDZ	<247..288	CDD:294084	13/54 (24%)
Pard3b	XP_006496361.1	DUF3534	2..74	CDD:338230
		PDZ_signaling	236..323	CDD:238492
		PDZ	415..504	CDD:214570	21/89 (24%)
		PDZ_signaling	536..624	CDD:238492	22/94 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900