Protein Alignment sprt and Pdzk1

DIOPT Version :9

• Sequence 1: NP_610683.1
• Gene: sprt / 246397
• FlyBaseID: FBgn0082585
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_001139473.1
• Gene: Pdzk1 / 59020
• MGIID: 1928901
• Length: 519
• Species: Mus musculus
• Alignment Length: 560
• Identity: 98/560 - (17%)
• Similarity: 176/560 - (31%)
• Gaps: 210/560 - (37%)

  Fly    61 HCSTTGRRRKGGS------LGGTLSSRSTRS--ESKELRSALQDREAVIQNLRIQLCLGKLPRPT 117
            |.......||.|:      |.|....::.::  :.|||..:  .|||.:.:        |.|
Mouse    68 HAQVVELVRKSGNSVTLLVLDGDSYEKAVKNQVDLKELDQS--QREAALND--------KKP--- 119

  Fly   118 GPPLDESEKPAAEQKLNRLKTEAENKRIKIKNLKSALEKLDITDNIDIRIRQAELEYALGREELQ 182
            ||.::.:.:|.|:.:|..|..|..:....:|.::                         |::.:.
Mouse   120 GPGMNGAVEPCAQPRLCYLVKEGNSFGFSLKTIQ-------------------------GKKGVY 159

  Fly   183 MLSIVEEARALQA--------------RLEKSKPEAQTLYNIISSGVSLSLHAVHATSGRWAVQQ 233
            :.:|:.:..|::|              .:|.:..| :.:..:..||..:....|...:.|...:|
Mouse   160 LTNIMPQGVAMKAGVLADDHLIEVNGENVENASHE-EVVEKVTKSGSRIMFLLVDKETARCHSEQ 223

  Fly   234 RTD-------------QP------------GFYVEWA----------------LEGDGLYKGDRI 257
            :|.             ||            |||:...                .|..||...|.:
Mouse   224 KTQFKRETASLKLLPHQPRVVVIKKGSNGYGFYLRAGPEQKGQIIKDIEPGSPAEAAGLKNNDLV 288

  Fly   258 LEINGRLVTGKSKEELQKQVGNSGKCQMVVLRKKSVPIPQKQLDQEKENNMRLQHRISYLEEQVR 322
            :.:|     |||.|.|.    :.|..:|:          :|..||.         .:..|:::..
Mouse   289 VAVN-----GKSVEALD----HDGVVEMI----------RKGGDQT---------TLLVLDKEAE 325

  Fly   323 ELQTVKEHHPSQQQQQQQQQQQNPQQNPQQNPQQTSSNQSQHVTSISISSPPSTPPE--KPLIF- 384
            .:.::....|....|.|:....:.::.|...|....:..|:          |:...|  ||.:.
Mouse   326 SIYSLARFSPLLYCQSQELPNGSVKEGPAPIPAPLEATGSE----------PTEDAEGHKPKLCR 380

  Fly   385 -----------------QRGNYITTLVGGKP------------IELMGDDMASTQTPPGHVTKTL 420
                             |.|:::..:..|.|            ||:.|:::  .:.|...|.:.:
Mouse   381 LLKEDDSYGFHLNAIRGQPGSFVKEVQQGGPADKAGLENEDVIIEVNGENV--QEEPYDRVVERI 443

  Fly   421 IKENTHIDLR--DRLSHMYSMPSKSLSASKISINSDSAYMQHHRRDKERHRDRQHRERPRDPLQQ 483
            .....|:.|.  .::::.|      ..|.||.|.|..|                      :||..
Mouse   444 KSSGKHVTLLVCGKMAYSY------FQAKKIPIVSSMA----------------------EPLVA 480

  Fly   484 QQQLHREHLMSTHARSVEHLNHYNGLDRRRDTPRQSESNT 523
            ......|    |.|.| ||..| ...||...|...|.||:
Mouse   481 GPDEKGE----TSAES-EHDAH-PAKDRTLSTASHSSSNS 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sprt	NP_610683.1	PDZ	<247..288	CDD:294084	12/40 (30%)
Pdzk1	NP_001139473.1	PDZ_signaling	7..87	CDD:238492	4/18 (22%)
		PDZ	132..212	CDD:214570	12/105 (11%)
		PDZ_signaling	242..320	CDD:238492	18/105 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	348..374		5/35 (14%)
		PDZ_signaling	376..455	CDD:238492	12/80 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	479..519		13/42 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900