Protein Alignment sprt and lnx2b

DIOPT Version :9

• Sequence 1: NP_610683.1
• Gene: sprt / 246397
• FlyBaseID: FBgn0082585
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_998105.2
• Gene: lnx2b / 564464
• ZFINID: ZDB-GENE-040426-2500
• Length: 678
• Species: Danio rerio
• Alignment Length: 613
• Identity: 116/613 - (18%)
• Similarity: 204/613 - (33%)
• Gaps: 185/613 - (30%)

  Fly    48 TNQETASTTTTSTH---CSTTGRRRKGGSLGGTLSSRSTRSESKELRSALQDREAVIQNLRIQLC 109
            |..:|:|..|..|.   |...|:...|              :...|   .:.::.|...|...:|
Zfish     2 TESKTSSLPTGVTWARVCKECGQCHDG--------------QDSHL---FEYQDEVDDELVCHIC 49

  Fly   110 LGKLPRPTGPPL--------------DESEKPAAEQKLNRLKTEAENKRIKIKNLKSALEKLDIT 160
            |..|.:|...|.              |:...|...|::...:..|.:  :.::||   |:||.:.
Zfish    50 LQPLLQPMDTPCGHTYCFQCLSNFLHDQDFCPVDRQRIQLQQCRASS--LLVRNL---LDKLAVL 109

  Fly   161 DNIDIRIRQAELEYALGREELQ---------MLSIVEEARALQARLEKSKPEAQTLYNIISSGVS 216
            ...     ::|.|.::.|.|||         ...:.|||.      .|.:|....|....|.| .
Zfish   110 CPF-----RSECELSMQRCELQPHLHNRCPAFKRLREEAE------RKKRPSWNELKGSKSDG-D 162

  Fly   217 LSLHAVHATSGRWAVQQRTDQPGFYVEWALEGDG----------------LYKGDRILEINGRLV 265
            |:......|.||.|......:||.......||:.                |::.|...::..|:|
Zfish   163 LADAKSAQTIGRTAQLSAPSEPGLVNPAFEEGEDDTPLRCSLVAEATVVELFREDPGEDLGLRIV 227

  Fly   266 TGKSKE----ELQKQVGNSGKCQMVVLRKKSVPIPQKQLDQEKENNMRLQHRISYLEEQVRELQT 326
            .||...    .:|:.|.:|     :|.|...:......|:....:...:.|.        |.:..
Zfish   228 GGKDTPLGNIVIQEIVRDS-----LVARDGKLAPGDHILEVNDVSLASISHS--------RAIAV 279

  Fly   327 VKEHHPSQQQQQQQQQQQNPQQNPQQNPQQTSSNQSQHVTSISISSPPSTPPEKPLIFQRGNYIT 391
            :::  |..:.:....|::..:..|:.:.|.::|..:|         .|||......:.|     .
Zfish   280 IRQ--PCSRLRLTVMQEKGFKPRPEHHTQPSASPPTQ---------SPSTNQNHGTVIQ-----V 328

  Fly   392 TLVGGKPIELMGDDMASTQTPPGHVTKTL-----------IKENTHI------DLRDRLSHMYSM 439
            |||..:..|.:|..:......||.....|           ::.|..:      |||      :..
Zfish   329 TLVKHERSEALGIKLIRKSEEPGVFILDLLPGGLAAKDGKLRNNDKVLGINGQDLR------HGT 387

  Fly   440 PSKS---LSASKISINSDSAYMQHHRRD-KERHRDRQHRERPRDPLQQQQQLHREHL------MS 494
            |..:   :.||::.:|    ::....:| .|...:.|.|...|.|..|..:.|.|::      .|
Zfish   388 PESAAQIIQASEMRVN----FVVMRLQDVSEEGGEGQSRGARRVPEPQYFRRHSEYMKEPPGGFS 448

  Fly   495 THARSVEHLNHYNGLDRRRDTPRQSESNTL------RARLPSDMRSVK----------------- 536
            :..::|          ..:..||||...|:      |:|||..:.||:
Zfish   449 SQEKTV----------TLKKEPRQSLGITIAGGRDCRSRLPVYITSVQPVGCLHRDGTVKTGDVL 503

  Fly   537 ------SLDFDSENESKPATETRTTRPT 558
                  .|...:.||:....:|:|.:.|
Zfish   504 LSINGIDLTHLTYNEAVTVLKTQTAQST 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sprt	NP_610683.1	PDZ	<247..288	CDD:294084	11/60 (18%)
lnx2b	NP_998105.2	RING	46..82	CDD:214546	6/35 (17%)
		PDZ_signaling	210..291	CDD:238492	15/95 (16%)
		PDZ_signaling	325..406	CDD:238492	17/95 (18%)
		PDZ_signaling	451..537	CDD:238492	18/91 (20%)
		PDZ_signaling	587..671	CDD:238492

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900